H-[15N]TYR-OH

Base Information

• Chemical Name: H-[15N]TYR-OH
• CAS No.: 35424-81-8
• Molecular Formula: C9H11NO3
• Molecular Weight: 182.185
• Hs Code.: 28459000
• Mol file: 35424-81-8.mol

Synonyms:L-4-Hydroxyphenylalanine-15N;H-[15N]Ttr-OH;

Chemical Property of H-[15N]TYR-OH

Chemical Property:

• Melting Point: >300 °C (dec.)(lit.)
• PSA: 83.55000
• LogP: 1.04690
• Storage Temp.: -15°C

Purity/Quality:

99% ^*data from raw suppliers

L-Tyrosine-15N ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26

MSDS Files:

SDS file from LookChem

Useful:

• Uses: L-Tyrosine-15N is labelled analogue of L-Tyrosine (T899975), one of the 22 proteinogenic amino acids that are used by cells to synthesize proteins. L-Tyrosine is biologically converted from L-phenylalanine and is in turn is converted to L-DOPA and further converted into the neurotransmitters: dopamine, norepinephrine, and epinephrine.

Technology Process of H-[15N]TYR-OH

There total 1 articles about H-[15N]TYR-OH which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.0%

sodium pyruvate (113-24-6) + phenol (108-95-2,27073-41-2) → L-<15N>tyrosine (35424-81-8)

Guidance literature:

With ¹⁵N-ammonium sulfate; In water; at 37 ℃; bacterial cells Erwinia herbicola, pH 8.5;

DOI:10.1021/jo00358a004

Reference yield: 98.0%

L-<15N>tyrosine (35424-81-8) → 4-((3H-diazirin-3-yl)methyl)phenol

Guidance literature:

With [bis(acetoxy)iodo]benzene; ammonia; potassium hydroxide; In methanol; at 0 ℃; for 2h;

DOI:10.1021/jacs.9b07035

Reference yield: 98.0%

L-<15N>tyrosine (35424-81-8) → 15N2-(4-((3H-diazirin-3-yl)methyl)phenol)

Guidance literature:

With [bis(acetoxy)iodo]benzene; ammonia; potassium hydroxide; In methanol; at 0 ℃; for 2h;

DOI:10.1021/jacs.9b07035

upstream raw materials:

sodium pyruvate

phenol

Downstream raw materials:

C₁₄H₁₉⁽¹⁵⁾NO₅

4-(2-methoxyethyl)phenol

Refernces