(R)-1,2,3,4-Tetrahydroisoquinoline-1-carboxylic acid

Base Information

Chemical Name:(R)-1,2,3,4-Tetrahydroisoquinoline-1-carboxylic acid
CAS No.:151004-93-2
Molecular Formula:C10H11 N O2
Molecular Weight:177.2
Hs Code.:2933499090
DSSTox Substance ID:DTXSID40424903
Nikkaji Number:J1.063.432F
Mol file:151004-93-2.mol

Synonyms:151004-93-2;(R)-1,2,3,4-Tetrahydroisoquinoline-1-carboxylic acid;(R)-1,2,3,4-Tetrahydro-Isoquinoline-1-Carboxylic Acid;(1R)-1,2,3,4-tetrahydroisoquinoline-1-carboxylic acid;1-Isoquinolinecarboxylic acid, 1,2,3,4-tetrahydro-, (1R)-;MFCD03426332;SCHEMBL574702;DTXSID40424903;OXFGRWIKQDSSLY-SECBINFHSA-N;(R)-1,2,3,4-TETRAHYDRO-1-ISOQUINOLINECARBOXYLIC ACID;CS-D0737;AKOS006277549;AC-29338;DS-17188;TS-02453;AM20120533;EN300-175863;A809105;(1R)-1,2,3,4-TETRAHYDROISOQUINOLINECARBOXYLIC ACID

Suppliers and Price of (R)-1,2,3,4-Tetrahydroisoquinoline-1-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(R)-1,2,3,4-Tetrahydroisoquinoline-1-carboxylicAcid
50mg
$ 110.00

Matrix Scientific
(R)-1,2,3,4-Tetrahydroisoquinoline-1-carboxylicacid 97%
250mg
$ 370.00

Matrix Scientific
(R)-1,2,3,4-Tetrahydroisoquinoline-1-carboxylicacid 97%
1g
$ 810.00

Labseeker
(R)-1,2,3,4-TETRAHYDRO-ISOQUINOLINE-1-CARBOXYLICACID 96
5g
$ 923.00

J&W Pharmlab
(R)-1,2,3,4-Tetrahydro-isoquinoline-1-carboxylicacid 96%
5g
$ 950.00

J&W Pharmlab
(R)-1,2,3,4-Tetrahydro-isoquinoline-1-carboxylicacid 96%
250mg
$ 133.00

J&W Pharmlab
(R)-1,2,3,4-Tetrahydro-isoquinoline-1-carboxylicacid 96%
100mg
$ 116.00

J&W Pharmlab
(R)-1,2,3,4-Tetrahydro-isoquinoline-1-carboxylicacid 96%
50mg
$ 98.00

J&W Pharmlab
(R)-1,2,3,4-Tetrahydro-isoquinoline-1-carboxylicacid 96%
500mg
$ 165.00

J&W Pharmlab
(R)-1,2,3,4-Tetrahydro-isoquinoline-1-carboxylicacid 96%
1g
$ 230.00

Total 38 raw suppliers

Chemical Property of (R)-1,2,3,4-Tetrahydroisoquinoline-1-carboxylic acid

Chemical Property:

Vapor Pressure:3.77E-06mmHg at 25°C
Melting Point:239-240 °C(Solv: water (7732-18-5); acetone (67-64-1))
Refractive Index:1.576
Boiling Point:370.7°Cat760mmHg
PKA:1.84±0.20(Predicted)
Flash Point:178°C
PSA：49.33000
Density:1.225g/cm³
LogP:1.28680
Storage Temp.:under inert gas (nitrogen or Argon) at 2–8 °C
XLogP3:-1.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:177.078978594
Heavy Atom Count:13
Complexity:205

Purity/Quality:

97% ^*data from raw suppliers

(R)-1,2,3,4-Tetrahydroisoquinoline-1-carboxylicAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CNC(C2=CC=CC=C21)C(=O)O
Isomeric SMILES:C1CN[C@H](C2=CC=CC=C21)C(=O)O

Technology Process of (R)-1,2,3,4-Tetrahydroisoquinoline-1-carboxylic acid

There total 7 articles about (R)-1,2,3,4-Tetrahydroisoquinoline-1-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: (R)-1,2,3,4-tetrahydroisoquinoline-1-carboxylic acid potassium salt

: 151004-93-2
(R)-1,2,3,4-tetrahydroisoquinoline-1-carboxylic acid

Guidance literature:: With hydrogenchloride; In water; pH=2-3; Green chemistry;

Reference yield: 86.0%

: 106181-28-6,950580-38-8
ethyl (+/-)-1,2,3,4-tetrahydroisoquinoline-1-carboxylate

: 151004-93-2
(R)-1,2,3,4-tetrahydroisoquinoline-1-carboxylic acid

Guidance literature:: With lipase B from Candida albicans; ammonium acetate; In ethanol; water; at 3 ℃; for 24h; pH=8.0; Enzymatic reaction;
DOI:10.1002/ejoc.200800789

Reference yield: 80.0%

: 106181-28-6,950580-38-8
ethyl (+/-)-1,2,3,4-tetrahydroisoquinoline-1-carboxylate

: 950580-38-8
(S)-ethyl 1,2,3,4-tetrahydroisoquinoline-1-carboxylate

: 950580-38-8
C₁₂H₁₅NO₂

: 151004-93-2
(R)-1,2,3,4-tetrahydroisoquinoline-1-carboxylic acid

Guidance literature:: With water; di-n-propylamine; lipase B from Candida antarctica; In toluene; acetonitrile; at 25 ℃; for 192h; Enzymatic reaction;
DOI:10.1016/j.tetasy.2007.05.016