ethyl 9-fluoro-5-methyl-1-oxo-6,7-dihydro-1H,5H-pyrido[3,2,1-ij]quinoline-2-carboxylate

Base Information

Chemical Name:ethyl 9-fluoro-5-methyl-1-oxo-6,7-dihydro-1H,5H-pyrido[3,2,1-ij]quinoline-2-carboxylate
CAS No.:42835-47-2
Molecular Formula:C₁₆H₁₆FNO₃
Molecular Weight:289.306
Hs Code.:
Mol file:42835-47-2.mol

Synonyms:9-fluoro-5-methyl-1-oxo-6,7-dihydro-1H,5H-pyrido[3,2,1-ij]quinoline-2-carboxylic acid ethyl ester

Suppliers and Price of ethyl 9-fluoro-5-methyl-1-oxo-6,7-dihydro-1H,5H-pyrido[3,2,1-ij]quinoline-2-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
Ethyl 9-fluoro-5-methyl-1-oxo-6,7-dihydro-1H,5H-pyrido[3,2,1-ij]quinoline-2-carboxylate
500mg
$ 237.00

Total 5 raw suppliers

Chemical Property of ethyl 9-fluoro-5-methyl-1-oxo-6,7-dihydro-1H,5H-pyrido[3,2,1-ij]quinoline-2-carboxylate

Chemical Property:

Purity/Quality:

98%min ^*data from raw suppliers

Ethyl 9-fluoro-5-methyl-1-oxo-6,7-dihydro-1H,5H-pyrido[3,2,1-ij]quinoline-2-carboxylate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses Flumequine Ethyl Ester is an impurity of Flumequine (F445000), a quinolone antibacterial.

Technology Process of ethyl 9-fluoro-5-methyl-1-oxo-6,7-dihydro-1H,5H-pyrido[3,2,1-ij]quinoline-2-carboxylate

There total 6 articles about ethyl 9-fluoro-5-methyl-1-oxo-6,7-dihydro-1H,5H-pyrido[3,2,1-ij]quinoline-2-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.1%

: 105450-09-7
Diethyl (2-methyl-6-fluorotetrahydro-quinolin-1-yl)methylenemalonate

: 42835-47-2
9-fluoro-5-methyl-1-oxo-6,7-dihydro-1H,5H-pyrido[3,2,1-ij]quinoline-2-carboxylic acid ethyl ester

Guidance literature:: With PPA; In toluene; at 110 ℃; for 6h;
DOI:10.1016/S0957-4166(99)00071-3

Reference yield:

: 42835-25-6,202349-45-9
flumequine

: 75-03-6
ethyl iodide

: 42835-47-2
9-fluoro-5-methyl-1-oxo-6,7-dihydro-1H,5H-pyrido[3,2,1-ij]quinoline-2-carboxylic acid ethyl ester

Guidance literature:: With potassium carbonate; In N,N-dimethyl-formamide; at 70 ℃; for 4h;

Reference yield:

: 42835-89-2
6-fluoro-1,2,3,4-tetrahydro-2-methylquinoline

: 42835-47-2
9-fluoro-5-methyl-1-oxo-6,7-dihydro-1H,5H-pyrido[3,2,1-ij]quinoline-2-carboxylic acid ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 97 percent / 2.5 h / 125 °C

2: 69.1 percent / polyphosphoric acid / toluene / 6 h / 110 °C

With PPA; In toluene;
DOI:10.1016/S0957-4166(99)00071-3