4-methoxy-3-(1-(2,2,2-trifluoroacetyl)pyrrolidin-3-yl)benzene-1-sulfonyl chloride

Base Information

Chemical Name:4-methoxy-3-(1-(2,2,2-trifluoroacetyl)pyrrolidin-3-yl)benzene-1-sulfonyl chloride
CAS No.:1374646-82-8
Molecular Formula:C₁₃H₁₃ClF₃NO₄S
Molecular Weight:371.765
Hs Code.:

Synonyms:4-methoxy-3-(1-(2,2,2-trifluoroacetyl)pyrrolidin-3-yl)benzene-1-sulfonyl chloride

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4-methoxy-3-(1-(2,2,2-trifluoroacetyl)pyrrolidin-3-yl)benzene-1-sulfonyl chloride

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Technology Process of 4-methoxy-3-(1-(2,2,2-trifluoroacetyl)pyrrolidin-3-yl)benzene-1-sulfonyl chloride

There total 2 articles about 4-methoxy-3-(1-(2,2,2-trifluoroacetyl)pyrrolidin-3-yl)benzene-1-sulfonyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 648901-36-4
2,2,2-trifluoro-1-[3-(2-methoxy-phenyl)-pyrrolidin-1-yl]-ethanone

: 1374646-82-8
4-methoxy-3-(1-(2,2,2-trifluoroacetyl)pyrrolidin-3-yl)benzene-1-sulfonyl chloride

Guidance literature:: With chlorosulfonic acid; In dichloromethane; at -5 - 20 ℃; for 19h;

Reference yield:

: 91246-24-1
3-(2-Methoxyphenyl)pyrrolidine

: 1374646-82-8
4-methoxy-3-(1-(2,2,2-trifluoroacetyl)pyrrolidin-3-yl)benzene-1-sulfonyl chloride

Guidance literature:: Multi-step reaction with 2 steps

1: dichloromethane / 18 h / -20 - 20 °C

2: chlorosulfonic acid / dichloromethane / 19 h / -5 - 20 °C

With chlorosulfonic acid; In dichloromethane;