N-(2-(difluoromethoxy)-5-methylphenyl)-4-methoxy-3-pyrrolidin-3-yl-benzenesulfonamide hydrochloride

Base Information

Chemical Name:N-(2-(difluoromethoxy)-5-methylphenyl)-4-methoxy-3-pyrrolidin-3-yl-benzenesulfonamide hydrochloride
CAS No.:1374646-75-9
Molecular Formula:C₁₉H₂₂F₂N₂O₄S*ClH
Molecular Weight:448.918
Hs Code.:

Synonyms:N-(2-(difluoromethoxy)-5-methylphenyl)-4-methoxy-3-pyrrolidin-3-yl-benzenesulfonamide hydrochloride

Suppliers and Price of N-(2-(difluoromethoxy)-5-methylphenyl)-4-methoxy-3-pyrrolidin-3-yl-benzenesulfonamide hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N-(2-(difluoromethoxy)-5-methylphenyl)-4-methoxy-3-pyrrolidin-3-yl-benzenesulfonamide hydrochloride

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of N-(2-(difluoromethoxy)-5-methylphenyl)-4-methoxy-3-pyrrolidin-3-yl-benzenesulfonamide hydrochloride

There total 4 articles about N-(2-(difluoromethoxy)-5-methylphenyl)-4-methoxy-3-pyrrolidin-3-yl-benzenesulfonamide hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1374646-83-9
N-(2-(difluoromethoxy)-5-methylphenyl)-4-methoxy-3-(1-(2,2,2-trifluoroacetyl)pyrrolidin-3-yl)benzenesulfonamide

: 1374646-75-9
N-(2-(difluoromethoxy)-5-methylphenyl)-4-methoxy-3-pyrrolidin-3-yl-benzenesulfonamide hydrochloride

Guidance literature:: N-(2-(difluoromethoxy)-5-methylphenyl)-4-methoxy-3-(1-(2,2,2-trifluoroacetyl)pyrrolidin-3-yl)benzenesulfonamide; With water; sodium hydroxide; In methanol; at 20 ℃; for 2h;

With ammonium chloride; In water;

With hydrogenchloride; In diethyl ether; dichloromethane;

Reference yield:

: 91246-24-1
3-(2-Methoxyphenyl)pyrrolidine

: 1374646-75-9
N-(2-(difluoromethoxy)-5-methylphenyl)-4-methoxy-3-pyrrolidin-3-yl-benzenesulfonamide hydrochloride

Guidance literature:: Multi-step reaction with 4 steps

1: dichloromethane / 18 h / -20 - 20 °C

2: chlorosulfonic acid / dichloromethane / 19 h / -5 - 20 °C

3: pyridine / 18 h / 20 °C

4: water; sodium hydroxide / methanol / 2 h / 20 °C

With pyridine; chlorosulfonic acid; water; sodium hydroxide; In methanol; dichloromethane;

Reference yield:

: 648901-36-4
2,2,2-trifluoro-1-[3-(2-methoxy-phenyl)-pyrrolidin-1-yl]-ethanone

: 1374646-75-9
N-(2-(difluoromethoxy)-5-methylphenyl)-4-methoxy-3-pyrrolidin-3-yl-benzenesulfonamide hydrochloride

Guidance literature:: Multi-step reaction with 3 steps

1: chlorosulfonic acid / dichloromethane / 19 h / -5 - 20 °C

2: pyridine / 18 h / 20 °C

3: water; sodium hydroxide / methanol / 2 h / 20 °C

With pyridine; chlorosulfonic acid; water; sodium hydroxide; In methanol; dichloromethane;