5-AMINO-PYRAZINE-2-CARBOXYLIC ACID

Base Information

• Chemical Name: 5-AMINO-PYRAZINE-2-CARBOXYLIC ACID
• CAS No.: 40155-43-9
• Molecular Formula: C5H5N3O2
• Molecular Weight: 139.114
• Hs Code.: 2933990090
• Mol file: 40155-43-9.mol

Synonyms:Pyrazinecarboxylicacid, 5-amino- (7CI,9CI);2-amino-5-pirazinecarboxylic acid .;5-aminopyrazine-2-carboxylic;5-amino-pyrazine-2-carboxylic acid;

Chemical Property of 5-AMINO-PYRAZINE-2-CARBOXYLIC ACID

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Melting Point: 283 °C (decomp)
• Refractive Index: 1.663
• Boiling Point: 431.778 °C at 760 mmHg
• PKA: 4.41±0.10(Predicted)
• Flash Point: 214.932 °C
• PSA: 89.10000
• Density: 1.533g/cm³
• LogP: 0.33820
• Storage Temp.: Sealed in dry,Store in freezer, under -20°C

Purity/Quality:

99% ^*data from raw suppliers

5-Aminopyrazine-2-carboxylicAcid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5-AMINO-PYRAZINE-2-CARBOXYLIC ACID

There total 3 articles about 5-AMINO-PYRAZINE-2-CARBOXYLIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

5-chloropyrazinoic acid (36070-80-1) → 5-amino-2-pyrazinecarboxylic acid (40155-43-9)

Guidance literature:

With ammonium hydroxide; at 100 ℃; for 0.5h; Microwave irradiation;

DOI:10.3390/molecules22101797

Reference yield:

5-amino-2-bromopyrazine (59489-71-3) + potassium cyanide (151-50-8) → 5-aminopyrazine-2-carboxamide (89323-09-1) + 5-amino-2-pyrazinecarboxylic acid (40155-43-9)

Guidance literature:

With ethanol;

DOI:10.1021/ja01176a058

Reference yield:

→ 5-amino-2-pyrazinecarboxylic acid (40155-43-9)

Guidance literature:

2-Amino-pyrazin-5,6-dicarbonsaeure, W. (geschlossenes Gefaess, 170-175grad);

DOI:10.1002/hlca.19640470323

upstream raw materials:

5-amino-2-bromopyrazine

potassium cyanide

5-chloropyrazinoic acid

Downstream raw materials:

benzyl 5-aminopyrazine-2-carboxylate

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