89323-09-1

Basic information

• Product Name: 5-AMINOPYRAZINE-2-CARBOXAMIDE
• Synonyms: 5-AMINOPYRAZINE-2-CARBOXAMIDE;Pyrazinecarboxamide, 5-amino- (7CI,9CI);2-Amino-5-carbamoylpyrazine;5-Amino-2-pyrazinecarboxamide
• CAS NO: 89323-09-1
• Molecular Formula: C₅H₆N₄O
• Molecular Weight: 138.12734
• Product Categories: AMIDE
• Mol File: 89323-09-1.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• CAS DataBase Reference: 5-AMINOPYRAZINE-2-CARBOXAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-AMINOPYRAZINE-2-CARBOXAMIDE(89323-09-1)
• EPA Substance Registry System: 5-AMINOPYRAZINE-2-CARBOXAMIDE(89323-09-1)

Safety Data

• Hazardous Substances Data: 89323-09-1(Hazardous Substances Data)

Usage

General Description

5-Aminopyrazine-2-carboxamide is a chemical compound with the molecular formula C5H5N5O. It is also known as 2-amino-5-cyanopyrazine and is commonly used as an intermediate in the synthesis of pharmaceutical drugs. 5-AMINOPYRAZINE-2-CARBOXAMIDE has been found to have biological activity against certain enzymes and has potential use as a therapeutic agent. 5-Aminopyrazine-2-carboxamide is also used in the production of agrochemicals and dyes, as well as in the manufacture of organic compounds. It is classified as a heterocyclic compound and is typically produced through synthetic methods in the laboratory.

Upstream product

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• 21279-64-1 5-chloro-pyrazine-2-carboxylic acid amide 
• 59489-71-3 5-amino-2-bromopyrazine 
• 151-50-8 potassium cyanide 

Relevant articles and documents

Alkylamino derivatives of pyrazinamide: Synthesis and antimycobacterial evaluation

A series of pyrazinamide derivatives with alkylamino substitution was designed, synthesized and tested for their ability to inhibit the growth of selected mycobacterial, bacterial and fungal strains. The target structures were prepared from the corresponding 5-chloro (1) or 6-chloropyrazine-2-carboxamide (2) by nucleophilic substitution of chlorine by various non-aromatic amines (alkylamines). To determine the influence of alkyl substitution, corresponding amino derivatives (1a, 2a) and compounds with phenylalkylamino substitution were prepared. Some of the compounds exerted antimycobacterial activity against Mycobacterium tuberculosis H37Rv significantly better than standard pyrazinamide and corresponding starting compounds (1 and 2). Basic structure-activity relationships are presented. Only weak antibacterial and no antifungal activity was detected.