(3aR,6aR)-octahydro-pyrrolo[3,4-b]pyrrole-5-carboxylic acid benzyl ester

Base Information

Chemical Name:(3aR,6aR)-octahydro-pyrrolo[3,4-b]pyrrole-5-carboxylic acid benzyl ester
CAS No.:948846-57-9
Molecular Formula:C₁₄H₁₈N₂O₂
Molecular Weight:246.309
Hs Code.:

Synonyms:(3aR,6aR)-octahydro-pyrrolo[3,4-b]pyrrole-5-carboxylic acid benzyl ester

Suppliers and Price of (3aR,6aR)-octahydro-pyrrolo[3,4-b]pyrrole-5-carboxylic acid benzyl ester

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of (3aR,6aR)-octahydro-pyrrolo[3,4-b]pyrrole-5-carboxylic acid benzyl ester

Chemical Property:

Purity/Quality:: ≥98% ^*data from raw suppliers

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Technology Process of (3aR,6aR)-octahydro-pyrrolo[3,4-b]pyrrole-5-carboxylic acid benzyl ester

There total 4 articles about (3aR,6aR)-octahydro-pyrrolo[3,4-b]pyrrole-5-carboxylic acid benzyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 39.4%

: 948846-56-8
(3aR,6aR)-octahydro-pyrrolo[3,4-b]pyrrole-1,5-dicarboxylic acid 5-benzyl ester 1-tert-butyl ester

: 948846-57-9
(3aR,6aR)-octahydro-pyrrolo[3,4-b]pyrrole-5-carboxylic acid benzyl ester

Guidance literature:: With trifluoroacetic acid; In dichloromethane; for 2h;
DOI:10.1021/jm900480x

Reference yield:

: 13139-17-8
N-(Benzyloxycarbonyloxy)succinimide

: 948846-57-9
(3aR,6aR)-octahydro-pyrrolo[3,4-b]pyrrole-5-carboxylic acid benzyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: dichloromethane / 17 - 27 °C

2: trifluoroacetic acid / dichloromethane / 2 h

With trifluoroacetic acid; In dichloromethane;

Reference yield:

: 370880-09-4,1018443-32-7
(3aR,6aR)-octahydro-pyrrolo[3,4-b]pyrrole-1-carboxylic acid tert-butyl ester

: 948846-57-9
(3aR,6aR)-octahydro-pyrrolo[3,4-b]pyrrole-5-carboxylic acid benzyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: dichloromethane / 17 - 27 °C

2: trifluoroacetic acid / dichloromethane / 2 h

With trifluoroacetic acid; In dichloromethane;