cis-endo-2,3-bis(hydroxymethyl)-7-anti-(phenylmethoxy)methylbicyclo[2.2.1]-hept-5-ene acetonide

Base Information

• Chemical Name: cis-endo-2,3-bis(hydroxymethyl)-7-anti-(phenylmethoxy)methylbicyclo[2.2.1]-hept-5-ene acetonide
• CAS No.: 1456713-09-9
• Molecular Formula: C₂₀H₂₆O₃
• Molecular Weight: 314.425

Synonyms:cis-endo-2,3-bis(hydroxymethyl)-7-anti-(phenylmethoxy)methylbicyclo[2.2.1]-hept-5-ene acetonide

Chemical Property of cis-endo-2,3-bis(hydroxymethyl)-7-anti-(phenylmethoxy)methylbicyclo[2.2.1]-hept-5-ene acetonide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of cis-endo-2,3-bis(hydroxymethyl)-7-anti-(phenylmethoxy)methylbicyclo[2.2.1]-hept-5-ene acetonide

There total 4 articles about cis-endo-2,3-bis(hydroxymethyl)-7-anti-(phenylmethoxy)methylbicyclo[2.2.1]-hept-5-ene acetonide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-Methoxypropene (116-11-0) + cis-endo-2,3-bis(hydroxymethyl)-7-anti-(phenylmethoxy)methylbicyclo[2.2.1]-hept-5-ene (1456713-08-8) → cis-endo-2,3-bis(hydroxymethyl)-7-anti-(phenylmethoxy)methylbicyclo[2.2.1]-hept-5-ene acetonide (1456713-09-9)

Guidance literature:

With 10-camphorsulfonic acid; In dichloromethane; at 0 - 20 ℃; for 6h;

DOI:10.1016/j.tet.2013.08.013

Reference yield:

Benzyloxymethyl chloride (3587-60-8) → cis-endo-2,3-bis(hydroxymethyl)-7-anti-(phenylmethoxy)methylbicyclo[2.2.1]-hept-5-ene acetonide (1456713-09-9)

Guidance literature:

Multi-step reaction with 4 steps

1: diethyl ether / -20 °C

2: diethyl ether / -10 - 0 °C

3: lithium aluminium tetrahydride / diethyl ether; tetrahydrofuran / 1.5 h / Inert atmosphere; Reflux

4: 10-camphorsulfonic acid / dichloromethane / 6 h / 0 - 20 °C

With lithium aluminium tetrahydride; 10-camphorsulfonic acid; In tetrahydrofuran; diethyl ether; dichloromethane;

DOI:10.1016/j.tet.2013.08.013

Reference yield:

5-(benzyloxymethyl)cyclopentadiene (39939-07-6) → cis-endo-2,3-bis(hydroxymethyl)-7-anti-(phenylmethoxy)methylbicyclo[2.2.1]-hept-5-ene acetonide (1456713-09-9)

Guidance literature:

Multi-step reaction with 3 steps

1: diethyl ether / -10 - 0 °C

2: lithium aluminium tetrahydride / diethyl ether; tetrahydrofuran / 1.5 h / Inert atmosphere; Reflux

3: 10-camphorsulfonic acid / dichloromethane / 6 h / 0 - 20 °C

With lithium aluminium tetrahydride; 10-camphorsulfonic acid; In tetrahydrofuran; diethyl ether; dichloromethane;

DOI:10.1016/j.tet.2013.08.013

upstream raw materials:

Benzyloxymethyl chloride

5-(benzyloxymethyl)cyclopentadiene

10-benzyloxymethyl-4-oxa-tricyclo[5.2.1.0^2,6]dec-8-en-3,5-dione

2-Methoxypropene

Downstream raw materials:

(7-(phenylmethoxy)methyl-3,3-dimethylhexahydro-1Hcyclopenta[e][1,3]-dioxepine-6,8-diyl)dimethanol

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 1456713-09-9 cis-endo-2,3-bis(hydroxymethyl)-7-anti-(phenylmethoxy)methylbicyclo[2.2.1]-hept-5-ene acetonide

Send

Send

Metric Ton KG G Pound L ML

Send

Send