[5-[4-(2,2-dimethylpropionyloxymethyl)benzylcarbamoyl]-3-(4-fluorophenyl)-1-isopropyl-4-phenyl-1H-pyrrol-2-ylmethyl]triphenylphosphonium bromide

Base Information

Chemical Name:[5-[4-(2,2-dimethylpropionyloxymethyl)benzylcarbamoyl]-3-(4-fluorophenyl)-1-isopropyl-4-phenyl-1H-pyrrol-2-ylmethyl]triphenylphosphonium bromide
CAS No.:855249-14-8
Molecular Formula:Br*C₅₂H₅₁FN₂O₃P
Molecular Weight:881.865
Hs Code.:

[5-[4-(2,2-dimethylpropionyloxymethyl)benzylcarbamoyl]-3-(4-fluorophenyl)-1-isopropyl-4-phenyl-1H-pyrrol-2-ylmethyl]triphenylphosphonium bromide

Synonyms:[5-[4-(2,2-dimethylpropionyloxymethyl)benzylcarbamoyl]-3-(4-fluorophenyl)-1-isopropyl-4-phenyl-1H-pyrrol-2-ylmethyl]triphenylphosphonium bromide

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Chemical Property of [5-[4-(2,2-dimethylpropionyloxymethyl)benzylcarbamoyl]-3-(4-fluorophenyl)-1-isopropyl-4-phenyl-1H-pyrrol-2-ylmethyl]triphenylphosphonium bromide

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Technology Process of [5-[4-(2,2-dimethylpropionyloxymethyl)benzylcarbamoyl]-3-(4-fluorophenyl)-1-isopropyl-4-phenyl-1H-pyrrol-2-ylmethyl]triphenylphosphonium bromide

There total 1 articles about [5-[4-(2,2-dimethylpropionyloxymethyl)benzylcarbamoyl]-3-(4-fluorophenyl)-1-isopropyl-4-phenyl-1H-pyrrol-2-ylmethyl]triphenylphosphonium bromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 855249-13-7
2,2-dimethylpropionic acid 4-({[4-(4-fluorophenyl)-5-hydroxymethyl-1-isopropyl-3-phenyl-1H-pyrrole-2-carbonyl]amino}methyl)benzyl ester

: 6399-81-1
triphenylphosphine hydrobromide

: 855249-14-8
[5-[4-(2,2-dimethylpropionyloxymethyl)benzylcarbamoyl]-3-(4-fluorophenyl)-1-isopropyl-4-phenyl-1H-pyrrol-2-ylmethyl]triphenylphosphonium bromide

Guidance literature:: With sodium tetrahydroborate; In dichloromethane; at 50 ℃; for 1.5h;

Reference yield: 94.0%

: 855249-14-8
[5-[4-(2,2-dimethylpropionyloxymethyl)benzylcarbamoyl]-3-(4-fluorophenyl)-1-isopropyl-4-phenyl-1H-pyrrol-2-ylmethyl]triphenylphosphonium bromide

: 124752-23-4
tert-butyl 2-[(4R,6S)-6-formyl-2,2-dimethyl-1,3-dioxan-4-yl]acetate

: 855249-15-9
2,2-dimethylpropionic acid 4-({[5-[2-(6-tert-butoxycarbonylmethyl-2,2-dimethyl-[1,3]dioxan-4-yl)vinyl]-4-(4-fluorophenyl)-1-isopropyl-3-phenyl-1H-pyrrole-2-carbonyl]amino}methyl)benzyl ester

Guidance literature:: [5-[4-(2,2-dimethylpropionyloxymethyl)benzylcarbamoyl]-3-(4-fluorophenyl)-1-isopropyl-4-phenyl-1H-pyrrol-2-ylmethyl]triphenylphosphonium bromide; With sodium hexamethyldisilazane; In tetrahydrofuran; dimethyl sulfoxide; at -78 ℃; for 0.0833333h;

tert-butyl 2-[(4R,6S)-6-formyl-2,2-dimethyl-1,3-dioxan-4-yl]acetate; In tetrahydrofuran; dimethyl sulfoxide; at -78 - 25 ℃; for 2h;

With ammonium chloride; In tetrahydrofuran; water; dimethyl sulfoxide;