(2Z,4E)-2,4,6-tris(4-methoxyphenyl)-6-oxo-2,4-hexadienenitrile

Base Information

• Chemical Name: (2Z,4E)-2,4,6-tris(4-methoxyphenyl)-6-oxo-2,4-hexadienenitrile
• CAS No.: 1428733-73-6
• Molecular Formula: C₂₇H₂₃NO₄
• Molecular Weight: 425.484
• Mol file: 1428733-73-6.mol

Synonyms:(2Z,4E)-2,4,6-tris(4-methoxyphenyl)-6-oxo-2,4-hexadienenitrile

Chemical Property of (2Z,4E)-2,4,6-tris(4-methoxyphenyl)-6-oxo-2,4-hexadienenitrile

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (2Z,4E)-2,4,6-tris(4-methoxyphenyl)-6-oxo-2,4-hexadienenitrile

There total 3 articles about (2Z,4E)-2,4,6-tris(4-methoxyphenyl)-6-oxo-2,4-hexadienenitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

sodium cyanide (773837-37-9) + 2,4,6-Trispyrylium perchlorate → (2Z,4E)-2,4,6-tris(4-methoxyphenyl)-6-oxo-2,4-hexadienenitrile (1428733-73-6)

Guidance literature:

In acetonitrile; at 20 ℃; for 16h; Amberlite IRA 910

DOI:10.1007/s00706-012-0825-2

Reference yield: 93.0%

CN(1-)*C3H9NPol(1+) + 2,4,6-Trispyrylium perchlorate → (2Z,4E)-2,4,6-tris(4-methoxyphenyl)-6-oxo-2,4-hexadienenitrile (1428733-73-6)

Guidance literature:

In acetonitrile; at 20 ℃; for 0.833333h; Amberlite IRA 910 Green chemistry;

DOI:10.1007/s00706-012-0825-2

Reference yield:

4-methoxy-benzaldehyde (123-11-5) + 1-(4-methoxyphenyl)ethanone (100-06-1) → (2Z,4E)-2,4,6-tris(4-methoxyphenyl)-6-oxo-2,4-hexadienenitrile (1428733-73-6)

Guidance literature:

Multi-step reaction with 2 steps

1.1: sulfuric acid / 1.5 h / 20 - 100 °C

1.2: 24 h

2.1: alumina / acetonitrile / 0.37 h / 20 °C

With sulfuric acid; alumina; In acetonitrile;

DOI:10.1080/00397911.2013.831103

upstream raw materials:

sodium cyanide

4-methoxy-benzaldehyde

1-(4-methoxyphenyl)ethanone