1H-Imidazole-4,5-dimethanol

Base Information

• Chemical Name: 1H-Imidazole-4,5-dimethanol
• CAS No.: 33457-48-6
• Molecular Formula: C5H8N2O2
• Molecular Weight: 128.131
• Hs Code.: 2933290090
• Mol file: 33457-48-6.mol

Synonyms:4,5-Di(hydroxymethyl)imidazole;Imidazole-4,5-dimethanol(7CI,8CI);

Chemical Property of 1H-Imidazole-4,5-dimethanol

Chemical Property:

• Vapor Pressure: 2.54E-10mmHg at 25°C
• Melting Point: 162 °C
• Refractive Index: 1.633
• Boiling Point: 487.6 °C at 760 mmHg
• PKA: 12.83±0.10(Predicted)
• Flash Point: 248.7 °C
• PSA: 69.14000
• Density: 1.446 g/cm³
• LogP: -0.60570
• Storage Temp.: 2-8°C

Purity/Quality:

97% ^*data from raw suppliers

(1H-Imidazole-4,5-diyl)dimethanol ^*data from reagent suppliers

Safty Information:

• Safety Statements: 24/25

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1H-Imidazole-4,5-dimethanol

There total 5 articles about 1H-Imidazole-4,5-dimethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.5%

4,5-dihydroxymethyl-1-triphenylmethylimidazole (77134-74-8) → 4,5-dihydroxymethylimidazole (33457-48-6) + triphenylmethyl alcohol (76-84-6)

Guidance literature:

With acetic acid; for 1.5h; Heating;

DOI:10.1139/v82-107

Reference yield:

LAH lithium aluminum hydride + dimethyl imidazole-4,5-dicarboxylate (3304-70-9) → 4,5-dihydroxymethylimidazole (33457-48-6)

Guidance literature:

In tetrahydrofuran;

Reference yield:

dimethyl imidazole-4,5-dicarboxylate (3304-70-9) → 4,5-dihydroxymethylimidazole (33457-48-6)

Guidance literature:

With lithium aluminium tetrahydride; diethyl ether;

upstream raw materials:

dimethyl imidazole-4,5-dicarboxylate

imidazole 4,5-dicarboxylic acid diethyl ester

4,5-dihydroxymethyl-1-triphenylmethylimidazole