sodium succinimidyl 6-(2-(2-sulfonatobenzaldehyde)hydrazono)nicotinate

Base Information

• Chemical Name: sodium succinimidyl 6-(2-(2-sulfonatobenzaldehyde)hydrazono)nicotinate
• CAS No.: 186305-11-3
• Molecular Formula: C₁₇H₁₃N₄O₇S*Na
• Molecular Weight: 440.369
• Mol file: 186305-11-3.mol

Synonyms:sodium succinimidyl 6-(2-(2-sulfonatobenzaldehyde)hydrazono)nicotinate

Chemical Property of sodium succinimidyl 6-(2-(2-sulfonatobenzaldehyde)hydrazono)nicotinate

Chemical Property:

Purity/Quality:

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MSDS Files:

Useful:

Technology Process of sodium succinimidyl 6-(2-(2-sulfonatobenzaldehyde)hydrazono)nicotinate

There total 1 articles about sodium succinimidyl 6-(2-(2-sulfonatobenzaldehyde)hydrazono)nicotinate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

1-hydroxy-pyrrolidine-2,5-dione (6066-82-6) + 6-hydrazinylnicotinic acid (133081-24-0) + sodium 2-formylbenzenesulfonate (1008-72-6) → sodium succinimidyl 6-(2-(2-sulfonatobenzaldehyde)hydrazono)nicotinate (186305-11-3)

Guidance literature:

6-hydrazinylnicotinic acid; sodium 2-formylbenzenesulfonate; at 20 ℃; for 3h;

1-hydroxy-pyrrolidine-2,5-dione; With dicyclohexyl-carbodiimide; at 20 ℃; for 19h; Reflux;

DOI:10.1016/j.ejmech.2019.112032

Reference yield: 75.0%

methyl 2-amino-6-(((tertiary-butoxy)carbonyl)amino)hexanoate hydrochloride + sodium succinimidyl 6-(2-(2-sulfonatobenzaldehyde)hydrazono)nicotinate (186305-11-3) → N-ε-(t-butoxycarbonyl)-N-α-(6-(2-(2-sulfonatobenzaldehyde)-hydrazono)nicotinoyl)lysine methyl ester

Guidance literature:

With N-ethyl-N,N-diisopropylamine; In DMF (N,N-dimethyl-formamide); at 20 ℃; for 15h;

Reference yield: 66.6%

sodium succinimidyl 6-(2-(2-sulfonatobenzaldehyde)hydrazono)nicotinate (186305-11-3) + (2-(2-nitro-1H-imidazol-1-yl)ethan-1-amine) (36717-77-8) → C18H16N7O6S(1-)*Na(1+)

Guidance literature:

With triethylamine; In N,N-dimethyl-formamide; for 4h; Reflux;

upstream raw materials:

1-hydroxy-pyrrolidine-2,5-dione

6-hydrazinylnicotinic acid

sodium 2-formylbenzenesulfonate

Downstream raw materials:

1-(N-(6-(2-(2-Sulfonatobenzaldehyde)hydrazono)-Nicotinyl))hexanediamine

2-[[[5-[[2,2-dimethyl-6-[(4-(3,4-methylenedioxyphenyl)-6-phenyl-2-pyridinyl)oxy]-1-hexanamino]carbonyl]-2-pyridinyl]hydrazono]methyl]-benzenesulfonic Acid

HYNIC-G₃-c(RGDfK)