1-(p-bromobenzyl)-2-t-butyl-4-(p-fluorophenyl)-6-phenylpyridinium trifluoromethanesulphonate

Base Information

• Chemical Name: 1-(p-bromobenzyl)-2-t-butyl-4-(p-fluorophenyl)-6-phenylpyridinium trifluoromethanesulphonate
• CAS No.: 107071-33-0
• Molecular Formula: CF₃O₃S*C₂₈H₂₆BrFN
• Molecular Weight: 624.494
• Mol file: 107071-33-0.mol

Synonyms:1-(p-bromobenzyl)-2-t-butyl-4-(p-fluorophenyl)-6-phenylpyridinium trifluoromethanesulphonate

Chemical Property of 1-(p-bromobenzyl)-2-t-butyl-4-(p-fluorophenyl)-6-phenylpyridinium trifluoromethanesulphonate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-(p-bromobenzyl)-2-t-butyl-4-(p-fluorophenyl)-6-phenylpyridinium trifluoromethanesulphonate

There total 3 articles about 1-(p-bromobenzyl)-2-t-butyl-4-(p-fluorophenyl)-6-phenylpyridinium trifluoromethanesulphonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

4-bromobenzylamine hydrochloride (26177-44-6) + 2-t-butyl-4-(p-fluorophenyl)-6-phenylpyrylium trifluoromethanesulphonate (107071-31-8) → 1-(p-bromobenzyl)-2-t-butyl-4-(p-fluorophenyl)-6-phenylpyridinium trifluoromethanesulphonate (107071-33-0)

Guidance literature:

With triethylamine; In ethanol; at 25 ℃; for 16h;

DOI:10.1039/P29860001331

Reference yield:

1-(4-fluorophenyl)-4,4-dimethylpent-1-en-3-one (80917-22-2) → 1-(p-bromobenzyl)-2-t-butyl-4-(p-fluorophenyl)-6-phenylpyridinium trifluoromethanesulphonate (107071-33-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 90 percent / 6 h / 100 °C

2: 75 percent / Et₃N / ethanol / 16 h / 25 °C

With triethylamine; In ethanol;

DOI:10.1039/P29860001331

Reference yield:

acetophenone (98-86-2) → 1-(p-bromobenzyl)-2-t-butyl-4-(p-fluorophenyl)-6-phenylpyridinium trifluoromethanesulphonate (107071-33-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 90 percent / 6 h / 100 °C

2: 75 percent / Et₃N / ethanol / 16 h / 25 °C

With triethylamine; In ethanol;

DOI:10.1039/P29860001331

upstream raw materials:

4-bromobenzylamine hydrochloride

2-t-butyl-4-(p-fluorophenyl)-6-phenylpyrylium trifluoromethanesulphonate

1-(4-fluorophenyl)-4,4-dimethylpent-1-en-3-one

acetophenone

Downstream raw materials:

4,4'-dibromobibenzyl

2-t-butyl-4-(p-fluorophenyl)-6-phenylpyridine

2-[4-(4-Bromo-benzyl)-phenyl]-6-tert-butyl-4-(4-fluoro-phenyl)-pyridine

2-[2-(4-Bromo-benzyl)-phenyl]-6-tert-butyl-4-(4-fluoro-phenyl)-pyridine