3-(4-Methoxyphenyl)isoxazole-5-carboxylic acid

Base Information

Chemical Name:3-(4-Methoxyphenyl)isoxazole-5-carboxylic acid
CAS No.:618383-47-4
Molecular Formula:C11H9NO4
Molecular Weight:219.19
Hs Code.:2934999090
DSSTox Substance ID:DTXSID50360641
Nikkaji Number:J2.135.332I
Wikidata:Q82142484
Mol file:618383-47-4.mol

Synonyms:3-(4-methoxyphenyl)isoxazole-5-carboxylic acid;618383-47-4;3-(4-Methoxyphenyl)-5-isoxazolecarboxylic acid;3-(4-methoxyphenyl)-1,2-oxazole-5-carboxylic acid;MFCD04124288;3-(4-Methoxy-phenyl)-isoxazole-5-carboxylic acid;SCHEMBL2730319;DTXSID50360641;WEFMAZCRNQZFAY-UHFFFAOYSA-N;BBL039451;STK341644;AKOS000302943;CS-W014767;11L-327S;SY079285;AM20060406;FT-0677357;3-(4-methoxyphenyl)isoxazole-5-carboxylicacid;EN300-92825;5-Isoxazolecarboxylicacid,3-(4-methoxyphenyl)-;3-(4-Methoxyphenyl)-5-isoxazole carboxylic acid;A868625;SR-01000368583;J-510727;SR-01000368583-1;Z369737740

Suppliers and Price of 3-(4-Methoxyphenyl)isoxazole-5-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3-(4-Methoxyphenyl)-5-isoxazolecarboxylicacid
25mg
$ 45.00

SynQuest Laboratories
3-(4-Methoxyphenyl)-5-isoxazolecarboxylic acid
1 g
$ 189.00

SynQuest Laboratories
3-(4-Methoxyphenyl)-5-isoxazolecarboxylic acid
500 mg
$ 164.00

SynQuest Laboratories
3-(4-Methoxyphenyl)-5-isoxazolecarboxylic acid
5 g
$ 418.00

SynChem
3-(4-Methoxyphenyl)isoxazole-5-carboxylic acid 95+%
10 g
$ 500.00

SynChem
3-(4-Methoxyphenyl)isoxazole-5-carboxylic acid 95+%
1 g
$ 100.00

SynChem
3-(4-Methoxyphenyl)isoxazole-5-carboxylic acid 95+%
5 g
$ 300.00

Matrix Scientific
3-(4-Methoxyphenyl)-5-isoxazolecarboxylic acid
500mg
$ 179.00

Crysdot
3-(4-Methoxyphenyl)isoxazole-5-carboxylicacid 95%
10g
$ 253.00

Chemenu
3-(4-Methoxyphenyl)-5-isoxazolecarboxylicacid 95%
10g
$ 238.00

Total 36 raw suppliers

Chemical Property of 3-(4-Methoxyphenyl)isoxazole-5-carboxylic acid

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Melting Point:223-225 °C
Refractive Index:1.57
Boiling Point:461.108 °C at 760 mmHg
PKA:2.24±0.10(Predicted)
Flash Point:232.67 °C
PSA：72.56000
Density:1.31 g/cm³
LogP:2.04840
Storage Temp.:2-8°C
XLogP3:1.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:3
Exact Mass:219.05315777
Heavy Atom Count:16
Complexity:250

Purity/Quality:

97% ^*data from raw suppliers

3-(4-Methoxyphenyl)-5-isoxazolecarboxylicacid ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=C(C=C1)C2=NOC(=C2)C(=O)O

Technology Process of 3-(4-Methoxyphenyl)isoxazole-5-carboxylic acid

There total 5 articles about 3-(4-Methoxyphenyl)isoxazole-5-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 206055-86-9
3-(4-methoxyphenyl)-5-(hydroxymethyl)isoxazole

: 618383-47-4
3-(4-methoxyphenyl)-5-isoxazolylcarboxylic acid

Guidance literature:: With jones reagent; In acetone; at 0 - 35 ℃; for 3.5h;
DOI:10.1002/jccs.200700092

Reference yield:

: 3717-21-3,3717-22-4,140461-28-5,140461-29-6,3235-04-9
p-methoxyl benzaldoxime

: 618383-47-4
3-(4-methoxyphenyl)-5-isoxazolylcarboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: chloramine-T trihydrate / 2-methyl-propan-2-ol; H₂O / 20 °C

2: copper(II) sulfate pentahydrate; copper; sodium hydroxide / 2-methyl-propan-2-ol; H₂O / 20 °C / pH 6

With sodium hydroxide; chloroamine-T; copper; copper(II) sulfate; In water; tert-butyl alcohol;
DOI:10.1021/jo050163b

Reference yield:

: 123-11-5
4-methoxy-benzaldehyde

: 618383-47-4
3-(4-methoxyphenyl)-5-isoxazolylcarboxylic acid

Guidance literature:: Multi-step reaction with 3 steps

1: hydroxylamine hydrochloride; sodium hydroxide / 2-methyl-propan-2-ol; H₂O / 20 °C

2: chloramine-T trihydrate / 2-methyl-propan-2-ol; H₂O / 20 °C

3: copper(II) sulfate pentahydrate; copper; sodium hydroxide / 2-methyl-propan-2-ol; H₂O / 20 °C / pH 6

With sodium hydroxide; hydroxylamine hydrochloride; chloroamine-T; copper; copper(II) sulfate; In water; tert-butyl alcohol;
DOI:10.1021/jo050163b