cis-2-ethyl-3-phenyl-oxirane

Base Information

• Chemical Name: cis-2-ethyl-3-phenyl-oxirane
• CAS No.: 73951-64-1
• Molecular Formula: C₁₀H₁₂O
• Molecular Weight: 148.205
• Mol file: 73951-64-1.mol

Synonyms:cis-2-ethyl-3-phenyl-oxirane

Chemical Property of cis-2-ethyl-3-phenyl-oxirane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of cis-2-ethyl-3-phenyl-oxirane

There total 14 articles about cis-2-ethyl-3-phenyl-oxirane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

(Z)-but-1-en-1-ylbenzene (1560-09-4) → cis-2-ethyl-3-phenyl-oxirane (73951-64-1)

Guidance literature:

With diphenylphosphinic anhydride; dihydrogen peroxide; potassium carbonate; In tetrahydrofuran; at -5 ℃; for 20h;

DOI:10.1016/0040-4039(94)88260-6

Reference yield:

1-phenylbut-1-ene (824-90-8) → (1S,2S)-1,2-epoxy-1-phenylbutane (33669-38-4,69140-50-7,69140-51-8,73951-64-1,73951-65-2) + (1S,2R)-1,2-epoxy-1-phenylbutane (174953-28-7)

Guidance literature:

With Di(2-ethylhexyl)phthalate; at 30 ℃; for 24h; pH=6.5; optical yield given as %ee; enantioselective reaction; aq. phosphate buffer;

DOI:10.1016/j.tetasy.2010.12.022

Reference yield:

cis-1-phenyl-1-propylene (766-90-5) → cis-2-ethyl-3-phenyl-oxirane (73951-64-1)

Guidance literature:

With 3-chloro-benzenecarboperoxoic acid; In dichloromethane; at 0 - 20 ℃;

DOI:10.1039/d1cc03117a

upstream raw materials:

1-phenylbut-1-ene

(Z)-but-1-en-1-ylbenzene

trans-1-phenyl-1-butene

α-(phenylthio)butyrophenone

Downstream raw materials:

erythro-1-phenyl-1,2-butanediol

threo-1-phenyl-1,2-butanediol

(1S,2R)-1,2-epoxy-1-phenylbutane