[(E)-5-Methoxy-3-(1-methoxy-1-methyl-ethoxy)-hexa-1,5-dienyl]-benzene

Base Information

• Chemical Name: [(E)-5-Methoxy-3-(1-methoxy-1-methyl-ethoxy)-hexa-1,5-dienyl]-benzene
• CAS No.: 148587-30-8
• Molecular Formula: C₁₇H₂₄O₃
• Molecular Weight: 276.376
• Mol file: 148587-30-8.mol

Synonyms:[(E)-5-Methoxy-3-(1-methoxy-1-methyl-ethoxy)-hexa-1,5-dienyl]-benzene

Chemical Property of [(E)-5-Methoxy-3-(1-methoxy-1-methyl-ethoxy)-hexa-1,5-dienyl]-benzene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of [(E)-5-Methoxy-3-(1-methoxy-1-methyl-ethoxy)-hexa-1,5-dienyl]-benzene

There total 1 articles about [(E)-5-Methoxy-3-(1-methoxy-1-methyl-ethoxy)-hexa-1,5-dienyl]-benzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

(E)-3-phenylpropenal (14371-10-9) + 2-Methoxypropene (116-11-0) → [(E)-5-Methoxy-3-(1-methoxy-1-methyl-ethoxy)-hexa-1,5-dienyl]-benzene (148587-30-8)

Guidance literature:

With tris(6,6,7,7,8,8,8-heptafluoro-2,2-dimethyl-3,5-octanedionato)ytterbium; acetic acid; In dichloromethane; for 18h; Ambient temperature;

DOI:10.1021/jo972073f

Reference yield: 88.0%

methanol (67-56-1) + [(E)-5-Methoxy-3-(1-methoxy-1-methyl-ethoxy)-hexa-1,5-dienyl]-benzene (148587-30-8) → [(E)-6-Bromo-5,5-dimethoxy-3-(1-methoxy-1-methyl-ethoxy)-hex-1-enyl]-benzene (201802-97-3)

Guidance literature:

With N-Bromosuccinimide; potassium carbonate; In dichloromethane; at 0 ℃;

DOI:10.1016/S0040-4020(97)01016-8

Reference yield:

[(E)-5-Methoxy-3-(1-methoxy-1-methyl-ethoxy)-hexa-1,5-dienyl]-benzene (148587-30-8) → 4-benzyl-cyclopent-2-enone

Guidance literature:

Multi-step reaction with 3 steps

1: 88 percent / NBS; K₂CO₃ / CH₂Cl₂ / 0 °C

2: Bu₃SnH; AIBN / benzene / 7 h / Heating

3: 314 mg / aq. HCl / tetrahydrofuran / 20 h / 20 °C

With hydrogenchloride; N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile); tri-n-butyl-tin hydride; potassium carbonate; In tetrahydrofuran; dichloromethane; benzene; 1: Addition / 2: Cyclization / 3: Hydrolysis;

DOI:10.1016/S0040-4020(97)01016-8

upstream raw materials:

(E)-3-phenylpropenal

2-Methoxypropene

Downstream raw materials:

[(E)-6-Bromo-5,5-dimethoxy-3-(1-methoxy-1-methyl-ethoxy)-hex-1-enyl]-benzene