3-(Chlorodifluoromethoxy)aniline

Base Information

Chemical Name:3-(Chlorodifluoromethoxy)aniline
CAS No.:39065-91-3
Molecular Formula:C7H6ClF2NO
Molecular Weight:193.581
Hs Code.:2922299090
DSSTox Substance ID:DTXSID50539734
Nikkaji Number:J2.601.907I
Wikidata:Q82415535
Mol file:39065-91-3.mol

Synonyms:3-(Chlorodifluoromethoxy)aniline;39065-91-3;3-[chloro(difluoro)methoxy]aniline;SCHEMBL10889608;DTXSID50539734;MFCD07777128;AKOS025311285;A824390

Suppliers and Price of 3-(Chlorodifluoromethoxy)aniline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
3-(CHLORODIFLUOROMETHOXY)ANILINE 95.00%
5G
$ 1263.01

American Custom Chemicals Corporation
3-(CHLORODIFLUOROMETHOXY)ANILINE 95.00%
1G
$ 705.57

AHH
3-(Chlorodifluoromethoxy)aniline 98%
5g
$ 366.00

Total 13 raw suppliers

Chemical Property of 3-(Chlorodifluoromethoxy)aniline

Chemical Property:

Vapor Pressure:0.0454mmHg at 25°C
Melting Point:69 °C
Refractive Index:1.525
Boiling Point:237.2 °C at 760 mmHg
PKA:3.53±0.10(Predicted)
Flash Point:97.3 °C
PSA：35.25000
Density:1.402 g/cm³
LogP:3.01790
XLogP3:2.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:193.0105978
Heavy Atom Count:12
Complexity:156

Purity/Quality:

97% ^*data from raw suppliers

3-(CHLORODIFLUOROMETHOXY)ANILINE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:
Statements: 20/21/22-36/37/38
Safety Statements: 26-36/37/39

MSDS Files:

Useful:

Canonical SMILES:C1=CC(=CC(=C1)OC(F)(F)Cl)N

Technology Process of 3-(Chlorodifluoromethoxy)aniline

There total 4 articles about 3-(Chlorodifluoromethoxy)aniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 25.0%

: 97608-47-4
2-chloro(chlorodifluoromethoxy) benzene

: 95-57-8
2-monochlorophenol

: 41735-81-3
orthoformic acid tris-(2-chloro-phenyl ester)

: 39065-91-3
3-(chlorodifluoromethoxy) aniline

Guidance literature:: With sodium amide; In ammonia; -28 deg C, 20 min; r.t., 1.5 h;

Reference yield:

: 95-57-8
2-monochlorophenol

: 39065-91-3
3-(chlorodifluoromethoxy) aniline

Guidance literature:: Multi-step reaction with 4 steps

1: 84.6 percent / NaOH / H₂O / 0.5 h / 90 °C

2: 88 percent / Cl₂ / CCl₄ / 12 h / Heating; Irradiation

3: 87 percent / HF / 2 h / 20 - 30 °C

4: 19 percent / NaNH₂ / liquid ammonia / -28 deg C, 20 min; r.t., 1.5 h

With sodium hydroxide; hydrogen fluoride; chlorine; sodium amide; In tetrachloromethane; ammonia; water;

Reference yield:

: 766-51-8
2-Chloroanisole

: 39065-91-3
3-(chlorodifluoromethoxy) aniline

Guidance literature:: Multi-step reaction with 3 steps

1: 88 percent / Cl₂ / CCl₄ / 12 h / Heating; Irradiation

2: 87 percent / HF / 2 h / 20 - 30 °C

3: 19 percent / NaNH₂ / liquid ammonia / -28 deg C, 20 min; r.t., 1.5 h

With hydrogen fluoride; chlorine; sodium amide; In tetrachloromethane; ammonia;