n-Methyl-4-(trifluoromethoxy)aniline

Base Information

Chemical Name:n-Methyl-4-(trifluoromethoxy)aniline
CAS No.:41419-59-4
Molecular Formula:C8H8F3NO
Molecular Weight:191.153
Hs Code.:2922299090
European Community (EC) Number:671-218-7
DSSTox Substance ID:DTXSID50353230
Nikkaji Number:J3.336.574H
Wikidata:Q72491939
Mol file:41419-59-4.mol

Synonyms:n-methyl-4-(trifluoromethoxy)aniline;41419-59-4;n1-methyl-4-(trifluoromethoxy)aniline;Methyl(4-trifluoromethoxyphenyl)amine;SCHEMBL856882;DTXSID50353230;MGCCWCLGIPNIBP-UHFFFAOYSA-O;4-trifluoromethoxy-N-methylaniline;N-methyl-4-trifluoromethoxyaniline;MFCD00052332;STK681082;AKOS000254677;FS-1135;Methyl-(4-trifluoromethoxy-phenyl)-amine;N-methyl-(4-trifluoromethoxyphenyl)amine;N-Methyl-4-(trifluoromethoxy)benzenamine;NCGC00334404-01;CS-0081121;FT-0676193;I10106;AB01326978-02;EN300-3022042;N-Methyl-4-(trifluoromethoxy)aniline, AldrichCPR;N-METHYL-N-[4-(TRIFLUOROMETHOXY)PHENYL]AMINE

Suppliers and Price of n-Methyl-4-(trifluoromethoxy)aniline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
N-Methyl-4-(trifluoromethoxy)aniline
500mg
$ 60.00

SynQuest Laboratories
N-Methyl-4-(trifluoromethoxy)aniline 95%
25 g
$ 432.00

SynQuest Laboratories
N-Methyl-4-(trifluoromethoxy)aniline 95%
1 g
$ 32.00

SynQuest Laboratories
N-Methyl-4-(trifluoromethoxy)aniline 95%
10 g
$ 234.00

Sigma-Aldrich
N-Methyl-4-(trifluoromethoxy)aniline AldrichCPR
250mg
$ 53.00

Matrix Scientific
N-Methyl-4-(trifluoromethoxy)aniline 97%
5g
$ 107.00

Crysdot
N-Methyl-4-(trifluoromethoxy)aniline 97%
25g
$ 311.00

American Custom Chemicals Corporation
N-METHYL-4-(TRIFLUOROMETHOXY)ANILINE 95.00%
5G
$ 1059.14

American Custom Chemicals Corporation
N-METHYL-4-(TRIFLUOROMETHOXY)ANILINE 95.00%
1G
$ 673.37

Alichem
N-Methyl-4-(trifluoromethoxy)aniline
25g
$ 326.56

Total 29 raw suppliers

Chemical Property of n-Methyl-4-(trifluoromethoxy)aniline

Chemical Property:

Vapor Pressure:0.442mmHg at 25°C
Refractive Index:1.487
Boiling Point:194.4 °C at 760 mmHg
Flash Point:71.4 °C
PSA：21.26000
Density:1.28 g/cm³
LogP:2.69990
XLogP3:3.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:191.05579836
Heavy Atom Count:13
Complexity:152

Purity/Quality:

97% ^*data from raw suppliers

N-Methyl-4-(trifluoromethoxy)aniline ^*data from reagent suppliers

Safty Information:

Pictogram(s): T, Xn
Hazard Codes:T,Xn,Xi
Statements: 20/21/22-36/37/38-43-36
Safety Statements: 26-36/37/39-36/37

MSDS Files:

Useful:

Canonical SMILES:CNC1=CC=C(C=C1)OC(F)(F)F

Technology Process of n-Methyl-4-(trifluoromethoxy)aniline

There total 11 articles about n-Methyl-4-(trifluoromethoxy)aniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 67-56-1
methanol

: 461-82-5
4-(trifluoromethoxy)aniline

: 41419-59-4
N-methyl-4-(trifluoromethoxy)aniline

Guidance literature:: With bis[dichloro(pentamethylcyclopentadienyl)iridium(III)]; sodium hydroxide; at 150 ℃; for 12h; Inert atmosphere; Schlenk technique; Green chemistry;
DOI:10.1039/c2ra21487c

Reference yield: 82.0%

: N-(4-(trifluoromethoxy)phenyl)-1-imidazolecarboxamide

: 41419-59-4
N-methyl-4-(trifluoromethoxy)aniline

Guidance literature:: With sodium tetrahydroborate; iodine; In tetrahydrofuran; at 20 - 66 ℃; for 4.5h;

Reference yield: 70.0%

: 2402-62-2
N,N-dimethyl-4-(trifluoromethoxy) aniline

: 41419-59-4
N-methyl-4-(trifluoromethoxy)aniline

: N-methyl-N-(4-(trifluoromethoxyl)phenyl)formamide

Guidance literature:: With sodium tetrafluoroborate; [Cu(salicylate)₂(NCMe)]₂; tetrabutyl-ammonium chloride; oxygen; In acetonitrile; at 40 ℃; Schlenk technique;
DOI:10.1002/cctc.201901962