2-(4-Bromophenyl)pyriding

Base Information

• Chemical Name: 2-(4-Bromophenyl)pyriding
• CAS No.: 63996-36-1
• Molecular Formula: C11H8 Br N
• Molecular Weight: 234.095
• Hs Code.: 29333990
• European Community (EC) Number: 807-953-9
• DSSTox Substance ID: DTXSID70363912
• Nikkaji Number: J1.092.822B
• Wikidata: Q72511267
• Mol file: 63996-36-1.mol

Synonyms:2-(4-Bromophenyl)pyridine

Chemical Property of 2-(4-Bromophenyl)pyriding

Chemical Property:

• Vapor Pressure: 0.000531mmHg at 25°C
• Melting Point: 61.0 to 65.0 °C
• Refractive Index: 1.606
• Boiling Point: 322.3 °C at 760 mmHg
• PKA: 4.29±0.25(Predicted)
• Flash Point: 148.7 °C
• PSA: 12.89000
• Density: 1.426 g/cm³
• LogP: 3.51110
• Storage Temp.: Sealed in dry,Room Temperature
• Solubility.: soluble in Toluene
• XLogP3: 3.3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• Exact Mass: 232.98401
• Heavy Atom Count: 13
• Complexity: 152

Purity/Quality:

99% ^*data from raw suppliers

2-(4-Bromophenyl)pyridine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=NC(=C1)C2=CC=C(C=C2)Br

Technology Process of 2-(4-Bromophenyl)pyriding

There total 44 articles about 2-(4-Bromophenyl)pyriding which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

2-bromo-pyridine (109-04-6) + 4-Bromophenylboronic acid (5467-74-3) → 2-(4-bromophenyl]pyridine (63996-36-1)

Guidance literature:

With palladium diacetate; potassium carbonate; In ethanol; water; at 80 ℃;

Reference yield: 92.0%

para-bromoacetophenone (99-90-1) + Trimethylenediamine (109-76-2,54018-94-9) → 2-(4-bromophenyl]pyridine (63996-36-1)

Guidance literature:

With oxygen; palladium diacetate; toluene-4-sulfonic acid; In tetrahydrofuran; for 10h; Reflux;

DOI:10.1016/j.tetlet.2016.12.075

Reference yield: 86.0%

1,4-bromoiodobenzene (589-87-7) + 2-tri-n-butylstannylpyridine (17997-47-6) → 2-(4-bromophenyl]pyridine (63996-36-1)

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; In toluene; at 110 ℃; for 16h; Inert atmosphere;

DOI:10.1039/d1tc02557k

upstream raw materials:

pyridine

acetic acid-(4-bromo-N-nitroso-anilide)

(4-bromophenyl)diazonium chloride

4-(pyridin-2-yl)aniline

Downstream raw materials:

2-(4'-(9'',9''-dihexylfluoren-2''-yl)phenyl)pyridine

10-(4-pyridin-2-yl-phenyl)-10H-phenoxazine

N-(4-(pyridin-2-yl)phenyl)-N,N-diphenylamine

9-(4-(pyridin-2-yl)phenyl)-9H-carbazole