(R)-(+)-dimethyl-2-benzyl- succinate

Base Information Edit

Chemical Name:(R)-(+)-dimethyl-2-benzyl- succinate
CAS No.:130272-52-5
Molecular Formula:C13H16O4
Molecular Weight:236.268
Hs Code.:
Mol file:130272-52-5.mol

Synonyms:Butanedioicacid, (phenylmethyl)-, dimethyl ester, (2R)- (9CI);Butanedioic acid,(phenylmethyl)-, dimethyl ester, (R)-;(2R)-(Phenylmethyl)butanedioic aciddimethyl ester;(R)-Dimethyl 2-phenylmethylbutanedioate;

Suppliers and Price of (R)-(+)-dimethyl-2-benzyl- succinate

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
(R)-(+)-DIMETHYL-2-BENZYL SUCCINATE 95.00%
5G
$ 909.56

Total 7 raw suppliers

Chemical Property of (R)-(+)-dimethyl-2-benzyl- succinate Edit

Chemical Property:

Vapor Pressure:0.000224mmHg at 25°C
Refractive Index:1.5
Boiling Point:325.9 °C at 760 mmHg
Flash Point:157.3 °C
PSA：52.60000
Density:1.113g/cm³
LogP:1.58140

Purity/Quality:

99% ^*data from raw suppliers

(R)-(+)-DIMETHYL-2-BENZYL SUCCINATE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of (R)-(+)-dimethyl-2-benzyl- succinate

There total 15 articles about (R)-(+)-dimethyl-2-benzyl- succinate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 65859-90-7
dimethyl (E)-benzylidenesuccinate

: 130272-52-5
dimethyl (R)-(+)-benzylsuccinate

: dimethyl (S)-(-)-benzylsuccinate

Guidance literature:: With N-Ph₂P-(R)-1-((S)-2-Ph₂P-ferrocenyl)ethylamine; hydrogen; bis(cycloocta-1,5-diene)rhodium(I) trifluoromethanesulfonate; In acetone; at 25 ℃; for 6h; under 15514.4 Torr; Title compound not separated from byproducts;
DOI:10.1021/jo048312y

Reference yield:

: 65859-90-7
dimethyl (E)-benzylidenesuccinate

: 130272-52-5
dimethyl (R)-(+)-benzylsuccinate

Guidance literature:: With hydrogen; bis(1,5-cyclooctadiene)rhodium(I) tetrafluoroborate; chiral monodentate phosphoramidite; In dichloromethane; at 20 ℃; for 10h; under 30402 Torr;
DOI:10.1021/ja063350f

Reference yield:

: 65756-82-3
Z-methyl 4-(phenyl)-3-methoxycarbonylbut-3-enoate

: 130272-52-5
dimethyl (R)-(+)-benzylsuccinate

Guidance literature:: Multi-step reaction with 3 steps

1: NaOH / methanol / 12 h / Heating

2: 10 percent / H₂; acetic acid / 10 percent Pd/C / 3 h / 75 °C

3: TsOH

With sodium hydroxide; hydrogen; toluene-4-sulfonic acid; acetic acid; palladium on activated charcoal; In methanol;
DOI:10.1016/S0957-4166(02)00822-4