1′-(diphenylphosphino)-1-bromoferrocene

Base Information

• Chemical Name: 1′-(diphenylphosphino)-1-bromoferrocene
• CAS No.: 185223-97-6
• Molecular Formula: C₂₂H₁₈BrFeP
• Molecular Weight: 449.11
• Mol file: 185223-97-6.mol

Synonyms:1′-(diphenylphosphino)-1-bromoferrocene

Chemical Property of 1′-(diphenylphosphino)-1-bromoferrocene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1′-(diphenylphosphino)-1-bromoferrocene

There total 2 articles about 1′-(diphenylphosphino)-1-bromoferrocene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

1,1'-dibromoferrocene (1293-65-8) + chloro-diphenylphosphine (1079-66-9,74391-44-9) → 1′-(diphenylphosphino)-1-bromoferrocene (185223-97-6)

Guidance literature:

1,1'-dibromoferrocene; With potassium tert-butylate; tert.-butyl lithium; Inert atmosphere; Schlenk technique;

chloro-diphenylphosphine; Inert atmosphere; Schlenk technique;

DOI:10.1039/c6cc02809h

Reference yield:

n-butyllithium (109-72-8,29786-93-4) + 1,1'-dibromoferrocene (1293-65-8) + chloro-diphenylphosphine (1079-66-9,74391-44-9) → 1′-(diphenylphosphino)-1-bromoferrocene (185223-97-6) + 1-bromo-2-(diphenylphosphino)ferrocene (1094756-39-4)

Guidance literature:

With 2,2,6,6-tetramethyl-piperidine; In tetrahydrofuran; Fe-compound lithiated in THF at -70°C with n-BuLi; 2,2,6,6-tetramethylpiperidine added; allowed to warm slowly; cooled to -50°C; quenched with organic ligand; mixt. of two isomeric products formed: 1,1'-compound:1,2-compound=60:40 molar ratio;

DOI:10.1016/j.inoche.2007.09.020

Reference yield: 95.0%

1′-(diphenylphosphino)-1-bromoferrocene (185223-97-6) + dimethyl sulfide borane (13292-87-0) → 1-(diphenylphosphino)-1'-bromferrocene borane

Guidance literature:

In tetrahydrofuran; at 20 ℃; for 1.5h; Inert atmosphere; Schlenk technique; Glovebox;

DOI:10.1039/c7dt02336g

upstream raw materials:

1,1'-dibromoferrocene

chloro-diphenylphosphine

n-butyllithium

Downstream raw materials:

1′-(diphenylphosphino)-1-aminoferrocene

1-diphenylphosphino-1'-bis(4-methoxyphenyl)phosphinoferrocene

1-diphenylphosphino-1'-bis(4-trifluoromethylphenyl)phosphinoferrocene

diethyl [1'-(diphenylphosphanyl)ferrocenyl]phosphonate