(Z)-3-(3,5-dimethoxyphenyl)-4,6-dimethoxy-1-(4-methoxybenzylidene)-1,3-dihydro-isobenzofuran

Base Information

• Chemical Name: (Z)-3-(3,5-dimethoxyphenyl)-4,6-dimethoxy-1-(4-methoxybenzylidene)-1,3-dihydro-isobenzofuran
• CAS No.: 1133711-28-0
• Molecular Formula: C₂₆H₂₆O₆
• Molecular Weight: 434.489
• Mol file: 1133711-28-0.mol

Synonyms:(Z)-3-(3,5-dimethoxyphenyl)-4,6-dimethoxy-1-(4-methoxybenzylidene)-1,3-dihydro-isobenzofuran

Chemical Property of (Z)-3-(3,5-dimethoxyphenyl)-4,6-dimethoxy-1-(4-methoxybenzylidene)-1,3-dihydro-isobenzofuran

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (Z)-3-(3,5-dimethoxyphenyl)-4,6-dimethoxy-1-(4-methoxybenzylidene)-1,3-dihydro-isobenzofuran

There total 2 articles about (Z)-3-(3,5-dimethoxyphenyl)-4,6-dimethoxy-1-(4-methoxybenzylidene)-1,3-dihydro-isobenzofuran which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

(E)-[2,4-dimethoxy-6-(4-methoxystyryl)phenyl]-(3,5-dimethoxyphenyl)methanol (1001258-87-2) → C26H26O6 (1111942-67-6) + (Z)-3-(3,5-dimethoxyphenyl)-4,6-dimethoxy-1-(4-methoxybenzylidene)-1,3-dihydro-isobenzofuran (1133711-28-0)

Guidance literature:

With copper dichloride; bis(benzonitrile)palladium(II) dichloride; In N,N-dimethyl-formamide; at 25 - 50 ℃; for 1h;

Reference yield: 35.0%

(E)-[2,4-dimethoxy-6-(4-methoxystyryl)phenyl]-(3,5-dimethoxyphenyl)methanol (1001258-87-2) → (Z)-3-(3,5-dimethoxyphenyl)-4,6-dimethoxy-1-(4-methoxybenzylidene)-1,3-dihydro-isobenzofuran (1133711-28-0)

Guidance literature:

With palladium(II) trifluoroacetate; sodium hydrogencarbonate; In dichloromethane; at 0 ℃; for 3h;

Reference yield: 41.0%

(Z)-3-(3,5-dimethoxyphenyl)-4,6-dimethoxy-1-(4-methoxybenzylidene)-1,3-dihydro-isobenzofuran (1133711-28-0) → 4,6-dimethoxy-3-(3,5-dimethoxyphenyl)-2-(4-methoxyphenyl)-1H-inden-1-one (885263-37-6)

Guidance literature:

With hydrogenchloride; In methanol; at 25 - 50 ℃; for 12h;

upstream raw materials:

(E)-[2,4-dimethoxy-6-(4-methoxystyryl)phenyl]-(3,5-dimethoxyphenyl)methanol

Downstream raw materials:

4,6-dimethoxy-3-(3,5-dimethoxyphenyl)-2-(4-methoxyphenyl)-1H-inden-1-one