4-methyltriphenylacetonitrile oxide

Base Information

• Chemical Name: 4-methyltriphenylacetonitrile oxide
• CAS No.: 137003-27-1
• Molecular Formula: C₂₁H₁₇NO
• Molecular Weight: 299.372
• Mol file: 137003-27-1.mol

Synonyms:4-methyltriphenylacetonitrile oxide

Chemical Property of 4-methyltriphenylacetonitrile oxide

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of 4-methyltriphenylacetonitrile oxide

There total 4 articles about 4-methyltriphenylacetonitrile oxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-methyltrityl chloride (23429-44-9) + fulminic acid ; silver-salt (5610-59-3) → 4-methyltriphenylacetonitrile oxide (137003-27-1)

Guidance literature:

In toluene; Yield given; 1) 0.5 h, 5 deg C, 2) RT, overnight;

DOI:10.1021/jo00026a024

Reference yield:

benzophenone (119-61-9) → 4-methyltriphenylacetonitrile oxide (137003-27-1)

Guidance literature:

Multi-step reaction with 3 steps

1: 1) Mg / 1) ether, 2) benzene

2: 90 percent / acetyl chloride / benzene / 1 h / Heating

3: toluene / 1) 0.5 h, 5 deg C, 2) RT, overnight

With magnesium; acetyl chloride; In toluene; benzene;

DOI:10.1021/jo00026a024

Reference yield:

para-bromotoluene (106-38-7) → 4-methyltriphenylacetonitrile oxide (137003-27-1)

Guidance literature:

Multi-step reaction with 3 steps

1: 1) Mg / 1) ether, 2) benzene

2: 90 percent / acetyl chloride / benzene / 1 h / Heating

3: toluene / 1) 0.5 h, 5 deg C, 2) RT, overnight

With magnesium; acetyl chloride; In toluene; benzene;

DOI:10.1021/jo00026a024

upstream raw materials:

4-methyltrityl chloride

fulminic acid ; silver-salt

benzophenone

para-bromotoluene

Refernces