1-(4-Aminophenyl)-1H-pyridin-2-one

Base Information

Chemical Name:1-(4-Aminophenyl)-1H-pyridin-2-one
CAS No.:13143-47-0
Molecular Formula:C11H10N2O
Molecular Weight:186.213
Hs Code.:2933399090
DSSTox Substance ID:DTXSID90468175
Wikidata:Q72440913
Mol file:13143-47-0.mol

Synonyms:13143-47-0;1-(4-AMINOPHENYL)-1H-PYRIDIN-2-ONE;1-(4-aminophenyl)pyridin-2(1H)-one;1-(4-aminophenyl)pyridin-2-one;1-(4-AMINO-PHENYL)-1H-PYRIDIN-2-ONE;2(1H)-Pyridinone, 1-(4-aminophenyl)-;1-(4-aminophenyl)-1,2-dihydropyridin-2-one;MFCD06659526;1-(4-AMINO-PHENYL)-1H-PYRIDINE-2-ONE;SCHEMBL76912;DTXSID90468175;LXFHLDJQBIZFOP-UHFFFAOYSA-N;AKOS006242624;AC-8460;CS-W006039;SB52779;DS-13594;SY115615;AM20050760;FT-0602115;EN300-268154;O10283;A888486;F1909-1611;Z1198169561

Suppliers and Price of 1-(4-Aminophenyl)-1H-pyridin-2-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
1-(4-Aminophenyl)-1H-pyridin-2-one
1g
$ 295.00

Crysdot
1-(4-Aminophenyl)-1H-pyridin-2-one 97%
5g
$ 579.00

Crysdot
1-(4-Aminophenyl)-1H-pyridin-2-one 97%
10g
$ 876.00

Chemenu
1-(4-aminophenyl)pyridin-2(1H)-one 95%
1g
$ 205.00

Biosynth Carbosynth
1-(4-Aminophenyl)-1H-pyridin-2-one
500 mg
$ 250.00

Biosynth Carbosynth
1-(4-Aminophenyl)-1H-pyridin-2-one
250 mg
$ 160.00

Biosynth Carbosynth
1-(4-Aminophenyl)-1H-pyridin-2-one
5 g
$ 1076.00

Biosynth Carbosynth
1-(4-Aminophenyl)-1H-pyridin-2-one
1 g
$ 380.00

Biosynth Carbosynth
1-(4-Aminophenyl)-1H-pyridin-2-one
2 g
$ 726.00

American Custom Chemicals Corporation
1-(4-AMINOPHENYL)-1H-PYRIDIN-2-ONE 95.00%
5MG
$ 505.97

Total 30 raw suppliers

Chemical Property of 1-(4-Aminophenyl)-1H-pyridin-2-one

Chemical Property:

Boiling Point:422.666 °C at 760 mmHg
PKA:4.89±0.10(Predicted)
Flash Point:209.421 °C
PSA：48.02000
Density:1.266 g/cm³
LogP:2.00090
Storage Temp.:under inert gas (nitrogen or Argon) at 2–8 °C
XLogP3:1.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:186.079312947
Heavy Atom Count:14
Complexity:275

Purity/Quality:

97% ^*data from raw suppliers

1-(4-Aminophenyl)-1H-pyridin-2-one ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=O)N(C=C1)C2=CC=C(C=C2)N
Uses 1-(4-Aminophenyl)-1H-pyridin-2-one is used in the synthesis of novel 2,3-dihydroquinazolin-4(1H)-one derivatives as potential fXa inhibitors.

Technology Process of 1-(4-Aminophenyl)-1H-pyridin-2-one

There total 5 articles about 1-(4-Aminophenyl)-1H-pyridin-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 142-08-5
2-hydroxypyridin

: 540-37-4
p-aminoiodobenzene

: 13143-47-0
1-(4-aminophenyl)pyridin-2(1H)-one

Guidance literature:: With 8-quinolinol; potassium carbonate; In N,N-dimethyl-formamide; Inert atmosphere; Reflux; Large scale;

Reference yield: 86.0%

: 53427-97-7
1-(4-nitrophenyl)pyridin-2(1H)-one

: 13143-47-0
1-(4-aminophenyl)pyridin-2(1H)-one

Guidance literature:: With water; ammonium chloride; zinc; In tetrahydrofuran;

Reference yield:

: 142-08-5,1199357-22-6
2-Pyridone

: 13143-47-0
1-(4-aminophenyl)pyridin-2(1H)-one

Guidance literature:: Multi-step reaction with 2 steps

1: potassium tert-butylate / N,N-dimethyl-formamide / 0 - 20 °C / Inert atmosphere

2: zinc; water; ammonium chloride / tetrahydrofuran

With potassium tert-butylate; water; ammonium chloride; zinc; In tetrahydrofuran; N,N-dimethyl-formamide;