8-benzyl-5,7-dioxo-5,6,7,8-tetrahydro-thiazolo[3,2-a]pyrimidinylium betaine

Base Information

• Chemical Name: 8-benzyl-5,7-dioxo-5,6,7,8-tetrahydro-thiazolo[3,2-a]pyrimidinylium betaine
• CAS No.: 50979-36-7
• Molecular Formula: C₁₃H₁₀N₂O₂S
• Molecular Weight: 258.301
• Mol file: 50979-36-7.mol

Synonyms:8-benzyl-5,7-dioxo-5,6,7,8-tetrahydro-thiazolo[3,2-a]pyrimidinylium betaine

Chemical Property of 8-benzyl-5,7-dioxo-5,6,7,8-tetrahydro-thiazolo[3,2-a]pyrimidinylium betaine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 8-benzyl-5,7-dioxo-5,6,7,8-tetrahydro-thiazolo[3,2-a]pyrimidinylium betaine

There total 3 articles about 8-benzyl-5,7-dioxo-5,6,7,8-tetrahydro-thiazolo[3,2-a]pyrimidinylium betaine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-benzylthiazol-2-amine (41593-98-0) + malonic acid bis-(2,4,6-trichloro-phenyl) ester (15781-70-1) → 8-benzyl-5,7-dioxo-5,6,7,8-tetrahydro-thiazolo[3,2-a]pyrimidinylium betaine (50979-36-7)

Guidance literature:

DOI:10.1002/jhet.5570100412

Reference yield:

N-(1,3-thiazol-2-yl)benzamide (13053-82-2) → 8-benzyl-5,7-dioxo-5,6,7,8-tetrahydro-thiazolo[3,2-a]pyrimidinylium betaine (50979-36-7)

Guidance literature:

Multi-step reaction with 2 steps

1: LiAlH₄ / tetrahydrofuran

With lithium aluminium tetrahydride; In tetrahydrofuran;

DOI:10.1002/jhet.5570100412

Reference yield:

benzoyl chloride (98-88-4) → 8-benzyl-5,7-dioxo-5,6,7,8-tetrahydro-thiazolo[3,2-a]pyrimidinylium betaine (50979-36-7)

Guidance literature:

Multi-step reaction with 3 steps

1: Et₃N / tetrahydrofuran

2: LiAlH₄ / tetrahydrofuran

With lithium aluminium tetrahydride; triethylamine; In tetrahydrofuran;

DOI:10.1002/jhet.5570100412

upstream raw materials:

N-benzylthiazol-2-amine

malonic acid bis-(2,4,6-trichloro-phenyl) ester

N-(1,3-thiazol-2-yl)benzamide

benzoyl chloride