(S)-3-Hydroxy-4,4-dimethyldihydrofuran-2(3H)-one

Base Information

Chemical Name:(S)-3-Hydroxy-4,4-dimethyldihydrofuran-2(3H)-one
CAS No.:5405-40-3
Molecular Formula:C₆H₁₀O₃
Molecular Weight:130.144
Hs Code.:2932209090
UNII:FD4U4CPB7D
DSSTox Substance ID:DTXSID801316664
Nikkaji Number:J94.837C
Mol file:5405-40-3.mol

Synonyms:5405-40-3;(S)-(+)-Pantolactone;(S)-3-Hydroxy-4,4-dimethyldihydrofuran-2(3H)-one;L-Pantolactone;(3S)-3-hydroxy-4,4-dimethyloxolan-2-one;(S)-pantolactone;Pantolactone, (S)-;2(3H)-Furanone, dihydro-3-hydroxy-4,4-dimethyl-, (3S)-;FD4U4CPB7D;(S)-2-Hydroxy-3,3-dimethyl-4-butanolide;EC 626-470-2;(3S)-dihydro-3-hydroxy-4,4-dimethyl-2(3H)-furanone;MFCD00216625;Pantolactons;l-Pantoyl lactone;(+)-pantolactone;(S)-pantoyl lactone;L-(+)-Pantolactone;UNII-FD4U4CPB7D;Pantolactone L-Form [MI];SCHEMBL1164243;(S)-(+)-Pantolactone, 97%;DTXSID801316664;BCP10328;AKOS015842117;CS-W013437;TS-01704;(3S)-3-hydroxy-4,4-dimethyl-2-oxolanone;(3S)-4,4-dimethyl-3-oxidanyl-oxolan-2-one;(S)-3-Hydroxy-4,4-dimethyl-dihydro-furan-2-one;3-(S)-Hydroxy-4,4-dimethyl-dihydro-furan-2-one;A829931;(3S)-3-hydroxy-4,4-dimethyl-tetrahydrofuran-2-one;(S)-3-hydroxy-4,4-dimethydihydrofuran-2-(3H)-one;2(3H)-Furanone, dihydro-3-hydroxy-4,4-dimethyl-, (S)-;Butyric acid, 2,4-dihydroxy-3,3-dimethyl-, .gamma.-lactone, ()-

Suppliers and Price of (S)-3-Hydroxy-4,4-dimethyldihydrofuran-2(3H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(S)?-?(+)?-?Pantolactone
500mg
$ 95.00

SynQuest Laboratories
(S)-(+)-Pantolactone 97%
10 g
$ 888.00

SynQuest Laboratories
(S)-(+)-Pantolactone 97%
5 g
$ 536.00

SynQuest Laboratories
(S)-(+)-Pantolactone 97%
1 g
$ 200.00

Sigma-Aldrich
(S)-(+)-Pantolactone 97%
1g
$ 213.00

Crysdot
(S)-3-Hydroxy-4,4-dimethyldihydrofuran-2(3H)-one 97%
25g
$ 594.00

Crysdot
(S)-3-Hydroxy-4,4-dimethyldihydrofuran-2(3H)-one 97%
10g
$ 297.00

Chem-Impex
(S)-(+)-Pantolactone,≥96.5%(GC) ≥96.5%(GC)
1G
$ 194.52

Chemenu
(S)-3-hydroxy-4,4-dimethyldihydrofuran-2(3H)-one 97%
10g
$ 281.00

Chemenu
(S)-3-hydroxy-4,4-dimethyldihydrofuran-2(3H)-one 97%
25g
$ 561.00

Total 86 raw suppliers

Chemical Property of (S)-3-Hydroxy-4,4-dimethyldihydrofuran-2(3H)-one

Chemical Property:

Vapor Pressure:0.018mmHg at 25°C
Melting Point:90-94 °C
Refractive Index:1.469
Boiling Point:224.61 °C at 760 mmHg
PKA:13.12±0.40(Predicted)
Flash Point:98.957 °C
PSA：46.53000
Density:1.166 g/cm³
LogP:-0.06970
Storage Temp.:2-8°C
Solubility.:Chloroform (Slightly), Methanol (Slightly), Water (Slightly)
Water Solubility.:Soluble in water, hardly soluble in alcohol.
XLogP3:0.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:130.062994177
Heavy Atom Count:9
Complexity:139

Purity/Quality:

99%, ^*data from raw suppliers

(S)?-?(+)?-?Pantolactone ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 41
Safety Statements: 26-39

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1(COC(=O)C1O)C
Isomeric SMILES:CC1(COC(=O)[C@H]1O)C
Uses (S)?-?(+)?-?Pantolactone is a versatile cyclic ester reactant used in the preparation of tunable ligands carbohydrate-derived diarylphosphinites for asymetric catalysis hydrovinylation of styrene derivatives.

Technology Process of (S)-3-Hydroxy-4,4-dimethyldihydrofuran-2(3H)-one

There total 66 articles about (S)-3-Hydroxy-4,4-dimethyldihydrofuran-2(3H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: C₇H₁₂O₂

: 79-50-5,599-04-2,5405-40-3,52126-90-6
(S)-pantolactone

Guidance literature:: With sodium tetrahydroborate; In acetic acid; for 0.5h;
DOI:10.1021/acs.joc.9b01426

Reference yield: 95.0%

: 13031-04-4
ketopantolactone

: 79-50-5,599-04-2,5405-40-3,52126-90-6
(S)-pantolactone

: 599-04-2
(R)-Pantolacton

Guidance literature:: With hydrogen; chloro(1,5-cyclooctadiene)rhodium(I) dimer; (2S,4S)-N-butoxycarbonyl-4-diphenylphosphino-2-diphenylphosphinomethylpyrrolidine; In toluene; at 50 ℃; for 45h; under 37503 Torr; Yields of byproduct given. Title compound not separated from byproducts;
DOI:10.1007/BF00816861