Technology Process of ethyl 2-((4-methoxyphenyl)amino)-1-(3-(piperidin-1-yl)propyl)-1H-imidazo[4,5-c]pyridine-6-carboxylate
There total 5 articles about ethyl 2-((4-methoxyphenyl)amino)-1-(3-(piperidin-1-yl)propyl)-1H-imidazo[4,5-c]pyridine-6-carboxylate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
potassium carbonate;
In
N,N-dimethyl-formamide;
at 65 ℃;
for 12h;
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 4-methylcyclohexene / palladium 10% on activated carbon / isopropyl alcohol / 12 h / 100 °C / Sealed tube
2: dicyclohexyl-carbodiimide / tetrahydrofuran / 12 h / 65 °C
3: potassium carbonate / N,N-dimethyl-formamide / 12 h / 65 °C
With
4-methylcyclohexene; potassium carbonate; dicyclohexyl-carbodiimide;
palladium 10% on activated carbon;
In
tetrahydrofuran; N,N-dimethyl-formamide; isopropyl alcohol;
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: hydrogen; lithium hydroxide / palladium 10% on activated carbon / water / 16 h / 40 - 70 °C / 2327.23 Torr
1.2: pH 3
2.1: potassium nitrate; sulfuric acid / 2.33 h / 20 - 75 °C
2.2: 12 h / 60 °C / Cooling with ice
2.3: Cooling with ice
3.1: 4-methylcyclohexene / palladium 10% on activated carbon / isopropyl alcohol / 12 h / 100 °C / Sealed tube
4.1: dicyclohexyl-carbodiimide / tetrahydrofuran / 12 h / 65 °C
5.1: potassium carbonate / N,N-dimethyl-formamide / 12 h / 65 °C
With
4-methylcyclohexene; sulfuric acid; hydrogen; potassium carbonate; potassium nitrate; dicyclohexyl-carbodiimide; lithium hydroxide;
palladium 10% on activated carbon;
In
tetrahydrofuran; water; N,N-dimethyl-formamide; isopropyl alcohol;