N-Boc-4-aminobutyric acid 1-methyl-2-[2-(2-methyl-[1,3]dioxolan-2-yl)-phenyl]-ethyl ester

Base Information

Chemical Name:N-Boc-4-aminobutyric acid 1-methyl-2-[2-(2-methyl-[1,3]dioxolan-2-yl)-phenyl]-ethyl ester
CAS No.:618068-92-1
Molecular Formula:C₂₂H₃₃NO₆
Molecular Weight:407.507
Hs Code.:

Synonyms:N-Boc-4-aminobutyric acid 1-methyl-2-[2-(2-methyl-[1,3]dioxolan-2-yl)-phenyl]-ethyl ester

Suppliers and Price of N-Boc-4-aminobutyric acid 1-methyl-2-[2-(2-methyl-[1,3]dioxolan-2-yl)-phenyl]-ethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N-Boc-4-aminobutyric acid 1-methyl-2-[2-(2-methyl-[1,3]dioxolan-2-yl)-phenyl]-ethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of N-Boc-4-aminobutyric acid 1-methyl-2-[2-(2-methyl-[1,3]dioxolan-2-yl)-phenyl]-ethyl ester

There total 3 articles about N-Boc-4-aminobutyric acid 1-methyl-2-[2-(2-methyl-[1,3]dioxolan-2-yl)-phenyl]-ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 44.0%

: 57294-38-9
N-(tert-butoxycarbonyl)-4-aminobutanoic acid

: 618068-80-7
1-[2-(2-methyl-[1,3]dioxolan-2-yl)phenyl]propan-2-ol

: 618068-92-1
N-Boc-4-aminobutyric acid 1-methyl-2-[2-(2-methyl-[1,3]dioxolan-2-yl)-phenyl]-ethyl ester

Guidance literature:: With dmap; dicyclohexyl-carbodiimide; In dichloromethane;
DOI:10.1021/ol035782q

Reference yield:

: 50777-64-5
2-(2-bromophenyl)-2-methyl-1,3-dioxolane

: 618068-92-1
N-Boc-4-aminobutyric acid 1-methyl-2-[2-(2-methyl-[1,3]dioxolan-2-yl)-phenyl]-ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1.1: Li / diethyl ether / 2 h

1.2: 64 percent / diethyl ether / 2 h

2.1: 44 percent / 1,3-dicyclohexylcarbodiimide; 4-(dimethylamino)pyridine / CH₂Cl₂

With dmap; lithium; dicyclohexyl-carbodiimide; In diethyl ether; dichloromethane;
DOI:10.1021/ol035782q

Reference yield:

: 2142-69-0
2-bromophenyl methyl ketone

: 618068-92-1
N-Boc-4-aminobutyric acid 1-methyl-2-[2-(2-methyl-[1,3]dioxolan-2-yl)-phenyl]-ethyl ester

Guidance literature:: Multi-step reaction with 3 steps

1.1: p-TsOH

2.1: Li / diethyl ether / 2 h

2.2: 64 percent / diethyl ether / 2 h

3.1: 44 percent / 1,3-dicyclohexylcarbodiimide; 4-(dimethylamino)pyridine / CH₂Cl₂

With dmap; lithium; toluene-4-sulfonic acid; dicyclohexyl-carbodiimide; In diethyl ether; dichloromethane;
DOI:10.1021/ol035782q