Boc-(S)-3-Amino-4-(3-bromo-phenyl)-butyric acid

Base Information

Chemical Name:Boc-(S)-3-Amino-4-(3-bromo-phenyl)-butyric acid
CAS No.:919988-44-6
Molecular Formula:C15H20 Br N O4
Molecular Weight:358.232
Hs Code.:
Mol file:919988-44-6.mol

Synonyms:BOC-(S)-3-AMINO-4-(3-BROMO-PHENYL)-BUTYRIC ACID;4-(3-bromophenyl)-3-[(tert-butoxycarbonyl)amino]butanoic acid;Boc-3-Amino-4-(3-bromophenyl)butyricacid;

Suppliers and Price of Boc-(S)-3-Amino-4-(3-bromo-phenyl)-butyric acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
4-(3-Bromophenyl)-3-((tert-butoxycarbonyl)amino)butanoicacid 95+%
1g
$ 474.00

Chemenu
4-(3-Bromophenyl)-3-((tert-butoxycarbonyl)amino)butanoicacid 95%
1g
$ 448.00

American Custom Chemicals Corporation
BOC-(S)-3-AMINO-4-(3-BROMOPHENYL)-BUTYRIC ACID 95.00%
5MG
$ 457.56

Ambeed
4-(3-Bromophenyl)-3-((tert-butoxycarbonyl)amino)butanoicacid 98%
1g
$ 647.00

Ambeed
4-(3-Bromophenyl)-3-((tert-butoxycarbonyl)amino)butanoicacid 98%
100mg
$ 173.00

Ambeed
4-(3-Bromophenyl)-3-((tert-butoxycarbonyl)amino)butanoicacid 98%
250mg
$ 259.00

Acrotein
4-(3-Bromophenyl)-3-(Boc-amino)butanoicacid 97%
0.5g
$ 302.50

Acrotein
4-(3-Bromophenyl)-3-(Boc-amino)butanoicacid 97%
0.25g
$ 192.50

Total 12 raw suppliers

Chemical Property of Boc-(S)-3-Amino-4-(3-bromo-phenyl)-butyric acid

Chemical Property:

PSA：89.62000
Density:1.370
LogP:3.37670
Storage Temp.:2-8°C

Purity/Quality:

97% ^*data from raw suppliers

4-(3-Bromophenyl)-3-((tert-butoxycarbonyl)amino)butanoicacid 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Boc-(S)-3-Amino-4-(3-bromo-phenyl)-butyric acid

There total 1 articles about Boc-(S)-3-Amino-4-(3-bromo-phenyl)-butyric acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 56.0%

: 919988-42-4
3-amino-4-(3-bromophenyl)butanoic acid

: 24424-99-5
di-tert-butyl dicarbonate

: 919988-44-6
4-(3-bromophenyl)-3-[(tert-butoxycarbonyl)amino]butanoic acid

Guidance literature:: 3-amino-4-(3-bromophenyl)butanoic acid; di-tert-butyl dicarbonate; With sodium hydroxide; In methanol; water; at 20 ℃; for 2h;

With hydrogenchloride; In methanol; water; pH=3;

Reference yield: 60.0%

: 67-56-1
methanol

: 919988-44-6
4-(3-bromophenyl)-3-[(tert-butoxycarbonyl)amino]butanoic acid

: 919988-45-7
methyl 4-(3-bromophenyl)-3-[(tert-butoxycarbonyl)amino]butanoate

Guidance literature:: With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; at 0 - 20 ℃; for 12h;

Reference yield:

: 919988-44-6
4-(3-bromophenyl)-3-[(tert-butoxycarbonyl)amino]butanoic acid

: methyl 4-(4'-(benzyloxy)-3'-{(2S)-2-{[(benzyloxy)carbonyl]amino}-3-oxo-3-[2-(trimethylsilyl)ethoxy]propyl}biphenyl-3-yl)-3-({(2S)-5-{[(benzyloxy)carbonyl]amino}-2-[(tert-butoxycarbonyl)amino]pentanoyl}amino)butanoate

Guidance literature:: Multi-step reaction with 4 steps

1: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / 12 h / 0 - 20 °C

2: caesium carbonate / (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride / 1-methyl-pyrrolidin-2-one; water / 6 h / 50 °C

3: hydrogenchloride / 1,4-dioxane / 3 h / 0 - 20 °C

4: N-ethyl-N,N-diisopropylamine; HATU / N,N-dimethyl-formamide / 0 - 20 °C

With hydrogenchloride; benzotriazol-1-ol; caesium carbonate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; HATU; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; In 1,4-dioxane; 1-methyl-pyrrolidin-2-one; water; N,N-dimethyl-formamide;