4-(Ethoxymethyl)-6-methyl-2-oxo-1,2-dihydropyridine-3-carbonitrile

Base Information

Chemical Name:4-(Ethoxymethyl)-6-methyl-2-oxo-1,2-dihydropyridine-3-carbonitrile
CAS No.:17718-67-1
Molecular Formula:C₁₀H₁₂N₂O₂
Molecular Weight:192.217
Hs Code.:
NSC Number:170634
DSSTox Substance ID:DTXSID50305390
ChEMBL ID:CHEMBL1567489

Synonyms:MLS000043787;4-(ethoxymethyl)-6-methyl-2-oxo-1,2-dihydropyridine-3-carbonitrile;SMR000020997;17718-67-1;NSC170634;ST037999;Opera_ID_1758;CHEMBL1567489;DTXSID50305390;NFLFYAQXZHFLQE-UHFFFAOYSA-N;HMS2291K08;STK663648;AKOS003273147;NSC-170634;SR-01000533032;SR-01000533032-1;4-Ethoxymethyl-6-methyl-2-oxo-1,2-dihydro-pyridine-3-carbonitrile;4-(Ethoxymethyl)-6-methyl-2-oxo-1,2-dihydro-3-pyridinecarbonitrile #

Suppliers and Price of 4-(Ethoxymethyl)-6-methyl-2-oxo-1,2-dihydropyridine-3-carbonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of 4-(Ethoxymethyl)-6-methyl-2-oxo-1,2-dihydropyridine-3-carbonitrile

Chemical Property:

Vapor Pressure:1.76E-05mmHg at 25°C
Boiling Point:363.8°Cat760mmHg
Flash Point:173.8°C
Density:1.15g/cm³
XLogP3:0.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:192.089877630
Heavy Atom Count:14
Complexity:358

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOCC1=C(C(=O)NC(=C1)C)C#N

Technology Process of 4-(Ethoxymethyl)-6-methyl-2-oxo-1,2-dihydropyridine-3-carbonitrile

There total 11 articles about 4-(Ethoxymethyl)-6-methyl-2-oxo-1,2-dihydropyridine-3-carbonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 56.0%

: 20754-01-2
1-ethoxy-2,4-pentanedione

: 107-91-5
cyanoacetic acid amide

: 17718-67-1
4-(ethoxymethyl)-6-methyl-2-oxo-1,2-dihydropyridine-3-carbonitrile

Guidance literature:: With piperidine; In ethanol; at 75 ℃; for 2h;
DOI:10.1021/jm801063n

Reference yield:

: 20754-01-2
1-ethoxy-2,4-pentanedione

: 107-91-5
cyanoacetic acid amide

: 17718-67-1
4-ethoxymethyl-2-hydroxy-6-methyl-nicotinonitrile

: 412035-47-3
6-ethoxymethyl-2-hydroxy-4-methyl-nicotinonitrile

Guidance literature:: With piperidine; ethanol;
DOI:10.1021/ja01874a068 DOI:10.1246/bcsj.19.1 DOI:10.1021/jo01176a016

Reference yield:

: 817-95-8
ethyl 2-ethoxyethanoate

: 67-64-1
acetone

: 107-91-5
cyanoacetic acid amide

: 17718-67-1
4-(ethoxymethyl)-6-methyl-2-oxo-1,2-dihydropyridine-3-carbonitrile

Guidance literature:: ethyl 2-ethoxyethanoate; acetone; With sodium hydride; In diethyl ether; acetone; at -5 - 0 ℃;

cyanoacetic acid amide; With piperidine; In ethanol; at 75 ℃;
DOI:10.1016/j.ejmech.2020.112034