2,2-Bis(4-fluorophenyl)acetic acid

Base Information

Chemical Name:2,2-Bis(4-fluorophenyl)acetic acid
CAS No.:361-63-7
Molecular Formula:C14H10F2O2
Molecular Weight:248.229
Hs Code.:2916399090
DSSTox Substance ID:DTXSID70542629
Wikidata:Q72445814
Mol file:361-63-7.mol

Synonyms:2,2-bis(4-fluorophenyl)acetic acid;361-63-7;Bis(4-fluorophenyl)acetic acid;Bis-(4-fluoro-phenyl)-acetic acid;bis(4-fluorophenyl) acetic acid;SCHEMBL67656;bis(4-fluoro phenyl)acetic acid;DTXSID70542629;bis-(4-fluorophenyl)-acetic acid;MCDCIWAVBWPRSP-UHFFFAOYSA-N;AMY37171;MFCD09743811;AKOS005063521;AS-61641;CS-0060237;W17756;A823152;J-519875

Suppliers and Price of 2,2-Bis(4-fluorophenyl)acetic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
2,2-Bis(4-fluorophenyl)aceticacid 95+%
5g
$ 832.00

Crysdot
2,2-Bis(4-fluorophenyl)aceticacid 95+%
1g
$ 299.00

Biosynth Carbosynth
Bis(4-fluorophenyl)acetic acid
5 g
$ 450.00

Biosynth Carbosynth
Bis(4-fluorophenyl)acetic acid
2 g
$ 350.00

Biosynth Carbosynth
Bis(4-fluorophenyl)acetic acid
1 g
$ 265.00

Biosynth Carbosynth
Bis(4-fluorophenyl)acetic acid
500 mg
$ 180.00

Biosynth Carbosynth
Bis(4-fluorophenyl)acetic acid
10 g
$ 550.00

American Custom Chemicals Corporation
BIS-(4-FLUOROPHENYL)ACETIC ACID 95.00%
5MG
$ 496.25

Alichem
2,2-Bis(4-fluorophenyl)aceticacid
1g
$ 239.12

AK Scientific
2,2-Bis(4-fluorophenyl)aceticacid
5g
$ 1458.80

Total 35 raw suppliers

Chemical Property of 2,2-Bis(4-fluorophenyl)acetic acid

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Melting Point:138 °C
Refractive Index:1.567
Boiling Point:347.087 °C at 760 mmHg
PKA:4.75±0.10(Predicted)
Flash Point:163.713 °C
PSA：37.30000
Density:1.312 g/cm³
LogP:3.18130
XLogP3:3.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:248.06488588
Heavy Atom Count:18
Complexity:258

Purity/Quality:

99% ^*data from raw suppliers

2,2-Bis(4-fluorophenyl)aceticacid 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1C(C2=CC=C(C=C2)F)C(=O)O)F

Technology Process of 2,2-Bis(4-fluorophenyl)acetic acid

There total 9 articles about 2,2-Bis(4-fluorophenyl)acetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 64-18-6
formic acid

: 365-24-2
4,4'-difluorobenzhydryl alcohol

: 361-63-7
2,2-bis(4-fluorophenyl)acetic acid

Guidance literature:: With sulfuric acid; at 15 - 16 ℃; for 2.1h;
DOI:10.1246/cl.1985.1733

Reference yield: 82.0%

: 462-06-6
fluorobenzene

: 298-12-4
Glyoxilic acid

: 361-63-7
2,2-bis(4-fluorophenyl)acetic acid

Guidance literature:: With sulfuric acid; acetic acid; at 80 ℃; for 12h;
DOI:10.1021/jm060381c

Reference yield:

: 352-34-1
4-fluoro-1-iodobenzene

: tert-butyl sodioacetate

: 541-50-4
2-acetoacetic acid

: 361-63-7
2,2-bis(4-fluorophenyl)acetic acid

: 405-50-5
p-Fluorophenylacetic acid

Guidance literature:: With toluene-4-sulfonic acid; iron(II) sulfate; Yield given. Multistep reaction. Yields of byproduct given; 1.) NH₃ (liquid), 20 min, 2.) H₂O, reflux, 4 h;