1-[5-benzyloxymethyl-1-(toluene-4-sulfonyl)vinyl-2,5-dihydro-1H-pyrrol-3-yl]ethanone

Base Information

Chemical Name:1-[5-benzyloxymethyl-1-(toluene-4-sulfonyl)vinyl-2,5-dihydro-1H-pyrrol-3-yl]ethanone
CAS No.:851315-52-1
Molecular Formula:C₂₃H₂₅NO₄S
Molecular Weight:411.522
Hs Code.:

Synonyms:1-[5-benzyloxymethyl-1-(toluene-4-sulfonyl)vinyl-2,5-dihydro-1H-pyrrol-3-yl]ethanone

Suppliers and Price of 1-[5-benzyloxymethyl-1-(toluene-4-sulfonyl)vinyl-2,5-dihydro-1H-pyrrol-3-yl]ethanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1-[5-benzyloxymethyl-1-(toluene-4-sulfonyl)vinyl-2,5-dihydro-1H-pyrrol-3-yl]ethanone

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1-[5-benzyloxymethyl-1-(toluene-4-sulfonyl)vinyl-2,5-dihydro-1H-pyrrol-3-yl]ethanone

There total 1 articles about 1-[5-benzyloxymethyl-1-(toluene-4-sulfonyl)vinyl-2,5-dihydro-1H-pyrrol-3-yl]ethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 851315-50-9
N-(1-benzyloxymethyl-4-hydroxybut-2-ynyl)-N-but-2-ynyl-4-methylbenzenesulfonamide

: 851315-52-1
1-[5-benzyloxymethyl-1-(toluene-4-sulfonyl)vinyl-2,5-dihydro-1H-pyrrol-3-yl]ethanone

Guidance literature:: With cyclopentadienylruthenium(II) trisacetonitrile hexafluorophosphate; malonic acid; In water; acetone; at 45 ℃; for 1h;
DOI:10.1021/ja043097o

Reference yield: 80.0%

: 851315-52-1
1-[5-benzyloxymethyl-1-(toluene-4-sulfonyl)vinyl-2,5-dihydro-1H-pyrrol-3-yl]ethanone

: 107-21-1
ethylene glycol

: 851315-54-3
2-benzyloxymethyl-4-(2-methyl-1,3-dioxolan-2-yl)-1-(toluene-4-sulfonyl)-3-vinyl-2,5-dihydro-1H-pyrrole

Guidance literature:: With toluene-4-sulfonic acid; for 8.5h; Heating;
DOI:10.1021/ja043097o

Reference yield:

: 851315-52-1
1-[5-benzyloxymethyl-1-(toluene-4-sulfonyl)vinyl-2,5-dihydro-1H-pyrrol-3-yl]ethanone

: 2-[2-hydroxymethyl-4-isopropenyl-1-(toluene-4-sulfonyl)pyrrolidin-3-yl]ethanol

Guidance literature:: Multi-step reaction with 8 steps

1.1: 80 percent / pTSA*H₂O / 8.5 h / Heating

2.1: Cy₂BH / tetrahydrofuran / 20 h / 20 °C

2.2: 82 percent / aq. NaOH; H₂O₂ / tetrahydrofuran / 5 h / 0 - 20 °C

3.1: 91 percent / imidazole / dimethylformamide / 15 h

4.1: 100 percent / H₂ / Pd(OH)2/C / methanol / 1.5 h

5.1: 100 percent / H₂ / Ir(cod)Py(PCy₃)PF₆ / CH₂Cl₂ / 6 h / 77572.2 Torr

6.1: 87 percent / pTSA / acetone / 24 h

7.1: 50 percent / imidazole / dimethylformamide / 48 h

8.1: tetrahydrofuran; pentane / 5 h / -78 °C

8.2: 87 percent / aq. HF / acetonitrile / 1 h

With 1H-imidazole; bis(cyclohexanyl)borane; hydrogen; toluene-4-sulfonic acid; palladium dihydroxide; Crabtree's catalyst; In tetrahydrofuran; methanol; dichloromethane; N,N-dimethyl-formamide; acetone; pentane;
DOI:10.1021/ja043097o