2-Methyl-2-(5-(trifluoromethyl)pyridin-2-yloxy)propanoic acid

Base Information

Chemical Name:2-Methyl-2-(5-(trifluoromethyl)pyridin-2-yloxy)propanoic acid
CAS No.:605680-62-4
Molecular Formula:C10H10 F3 N O3
Molecular Weight:249.19
Hs Code.:2933399090
DSSTox Substance ID:DTXSID10582645
Nikkaji Number:J2.533.441H
Wikidata:Q82474132
Mol file:605680-62-4.mol

Synonyms:605680-62-4;2-Methyl-2-(5-(trifluoromethyl)pyridin-2-yloxy)propanoic acid;2-methyl-2-[5-(trifluoromethyl)pyridin-2-yl]oxypropanoic acid;2-Methyl-2-[(5-trifluoromethylpyridin-2-yl)oxy]propionic acid;2-Methyl-2-((5-(trifluoromethyl)pyridin-2-yl)oxy)propanoic acid;2-methyl-2-{[5-(trifluoromethyl)pyridin-2-yl]oxy}propanoic acid;Propanoic acid, 2-methyl-2-[[5-(trifluoromethyl)-2-pyridinyl]oxy]-;Propanoic acid,2-methyl-2-[[5-(trifluoromethyl)-2-pyridinyl]oxy]-;SCHEMBL201045;O-TOLYLSULFANYL-ACETICACID;DTXSID10582645;MFCD11035896;AKOS015969362;AS-53415;CS-0003969;P16455;2-Methyl-2-(5-trifluoromethyl-2-pyridyloxy)propionic Acid;2-Methyl-2-(5-(trifluoromethyl)pyridin-2-yloxy)propanoicacid;2-Methyl-2-[(5-trifluoromethylpyridin-2-yl)oxy]propionicacid;2-Methyl-2-[[5-(trifluoromethyl)-2-pyridinyl]oxy]-propanoic acid

Suppliers and Price of 2-Methyl-2-(5-(trifluoromethyl)pyridin-2-yloxy)propanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
2-Methyl-2-(5-(trifluoromethyl)pyridin-2-yloxy)propanoicacid 95+%
1g
$ 353.00

Chemenu
2-methyl-2-((5-(trifluoromethyl)pyridin-2-yl)oxy)propanoicacid 95%
1g
$ 333.00

American Custom Chemicals Corporation
2-METHYL-2-(5-(TRIFLUOROMETHYL)PYRIDIN-2-YLOXY)PROPANOIC ACID 95.00%
5G
$ 1114.58

Alichem
2-Methyl-2-(5-(trifluoromethyl)pyridin-2-yloxy)propanoicacid
1g
$ 400.00

Activate Scientific
2-Methyl-2-(5-(trifluoromethyl)pyridin-2-yloxy)propanoicacid 95%
250 mg
$ 204.00

Total 24 raw suppliers

Chemical Property of 2-Methyl-2-(5-(trifluoromethyl)pyridin-2-yloxy)propanoic acid

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Boiling Point:306.607oC at 760 mmHg
Flash Point:139.231oC
PSA：59.42000
Density:1.352g/cm3
LogP:2.34240
Storage Temp.:2-8°C
XLogP3:2.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:3
Exact Mass:249.06127767
Heavy Atom Count:17
Complexity:291

Purity/Quality:

98%Min ^*data from raw suppliers

2-Methyl-2-(5-(trifluoromethyl)pyridin-2-yloxy)propanoicacid 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C(=O)O)OC1=NC=C(C=C1)C(F)(F)F

Technology Process of 2-Methyl-2-(5-(trifluoromethyl)pyridin-2-yloxy)propanoic acid

There total 5 articles about 2-Methyl-2-(5-(trifluoromethyl)pyridin-2-yloxy)propanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 913849-17-9
ethyl 2-methyl-2-{[5-(trifluoromethyl)pyridin-2-yl]oxy}propanoate

: 605680-62-4
2-methyl-2-{[5-(trifluoromethyl)pyridin-2-yl]oxy}propanoic acid

: 605681-37-6
2-ethoxy-5-trifluoromethylpyridine

Guidance literature:: ethyl 2-methyl-2-{[5-(trifluoromethyl)pyridin-2-yl]oxy}propanoate; With sodium hydroxide; water; In tetrahydrofuran; for 22h; Heating / reflux;

With hydrogenchloride; In water; for 0.166667h;

Reference yield:

: 913849-17-9
ethyl 2-methyl-2-{[5-(trifluoromethyl)pyridin-2-yl]oxy}propanoate

: 605680-62-4
2-methyl-2-{[5-(trifluoromethyl)pyridin-2-yl]oxy}propanoic acid

Guidance literature:: With sodium hydroxide; In water; acetonitrile; at 50 ℃;
DOI:10.1021/jm060996+

Reference yield:

: 52334-81-3
2-chloro-5-trifluoromethylpyridine

: 80-55-7
ethyl 2-hydroxy-2,2-dimethylethanoate

: 605680-62-4
2-methyl-2-{[5-(trifluoromethyl)pyridin-2-yl]oxy}propanoic acid

Guidance literature:: ethyl 2-hydroxy-2,2-dimethylethanoate; With potassium hexamethylsilazane; In tetrahydrofuran; at -70 - -62 ℃; for 0.5h;

2-chloro-5-trifluoromethylpyridine; In tetrahydrofuran; at -62 - 20 ℃; for 16h;

With sodium hydroxide; In tetrahydrofuran; water; for 22h; Heating / reflux;