1,4-diacetyl-3-(2-bromo-4-methoxy-5-methoxymethoxy-3-methylphenylmethyl)-2,5-piperazinedione

Base Information

Chemical Name:1,4-diacetyl-3-(2-bromo-4-methoxy-5-methoxymethoxy-3-methylphenylmethyl)-2,5-piperazinedione
CAS No.:628718-17-2
Molecular Formula:C₁₉H₂₃BrN₂O₇
Molecular Weight:471.305
Hs Code.:

Synonyms:1,4-diacetyl-3-(2-bromo-4-methoxy-5-methoxymethoxy-3-methylphenylmethyl)-2,5-piperazinedione

Suppliers and Price of 1,4-diacetyl-3-(2-bromo-4-methoxy-5-methoxymethoxy-3-methylphenylmethyl)-2,5-piperazinedione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1,4-diacetyl-3-(2-bromo-4-methoxy-5-methoxymethoxy-3-methylphenylmethyl)-2,5-piperazinedione

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1,4-diacetyl-3-(2-bromo-4-methoxy-5-methoxymethoxy-3-methylphenylmethyl)-2,5-piperazinedione

There total 5 articles about 1,4-diacetyl-3-(2-bromo-4-methoxy-5-methoxymethoxy-3-methylphenylmethyl)-2,5-piperazinedione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 3027-05-2
N,N'-diacetylpiperazin-2,5-dione

: 628718-17-2
1,4-diacetyl-3-(2-bromo-4-methoxy-5-methoxymethoxy-3-methylphenylmethyl)-2,5-piperazinedione

Guidance literature:: Multi-step reaction with 3 steps

1: 6.749 g / potassium tert-butoxide / 2-methyl-propan-2-ol; dimethylformamide / 1 h / 25 °C

2: 100 percent / H₂ / Rh/C / propan-2-ol / 19 h / 760 Torr

3: 4.106 g / pyridine; DMAP / 1 h / 25 °C

With pyridine; dmap; potassium tert-butylate; hydrogen; Rh on carbon; In N,N-dimethyl-formamide; isopropyl alcohol; tert-butyl alcohol;
DOI:10.1248/cpb.51.821

Reference yield:

: 287117-31-1
2-bromo-5-hydroxy-4-methoxy-3-methylbenzaldehyde

: 628718-17-2
1,4-diacetyl-3-(2-bromo-4-methoxy-5-methoxymethoxy-3-methylphenylmethyl)-2,5-piperazinedione

Guidance literature:: Multi-step reaction with 4 steps

1: 100 percent / K₂CO₃ / dimethylformamide / 1 h / 25 °C

2: 6.749 g / potassium tert-butoxide / 2-methyl-propan-2-ol; dimethylformamide / 1 h / 25 °C

3: 100 percent / H₂ / Rh/C / propan-2-ol / 19 h / 760 Torr

4: 4.106 g / pyridine; DMAP / 1 h / 25 °C

With pyridine; dmap; potassium tert-butylate; hydrogen; potassium carbonate; Rh on carbon; In N,N-dimethyl-formamide; isopropyl alcohol; tert-butyl alcohol;
DOI:10.1248/cpb.51.821

Reference yield:

: 628718-95-6
2-bromo-4-methoxy-5-methoxymethoxy-3-methylbenzaldehyde

: 628718-17-2
1,4-diacetyl-3-(2-bromo-4-methoxy-5-methoxymethoxy-3-methylphenylmethyl)-2,5-piperazinedione

Guidance literature:: Multi-step reaction with 3 steps

1: 6.749 g / potassium tert-butoxide / 2-methyl-propan-2-ol; dimethylformamide / 1 h / 25 °C

2: 100 percent / H₂ / Rh/C / propan-2-ol / 19 h / 760 Torr

3: 4.106 g / pyridine; DMAP / 1 h / 25 °C

With pyridine; dmap; potassium tert-butylate; hydrogen; Rh on carbon; In N,N-dimethyl-formamide; isopropyl alcohol; tert-butyl alcohol;
DOI:10.1248/cpb.51.821