3-(4-{5-[(4-Carbamoyl-4-phenylpiperidin-1-yl) carbonyl]-3-(2,4-dichlorophenyl)thien-2-yl}phenoxy)propyl methanesulphonate

Base Information

Chemical Name:3-(4-{5-[(4-Carbamoyl-4-phenylpiperidin-1-yl) carbonyl]-3-(2,4-dichlorophenyl)thien-2-yl}phenoxy)propyl methanesulphonate
CAS No.:1207203-51-7
Molecular Formula:C₃₃H₃₂Cl₂N₂O₆S₂
Molecular Weight:687.665
Hs Code.:

Synonyms:3-(4-{5-[(4-Carbamoyl-4-phenylpiperidin-1-yl) carbonyl]-3-(2,4-dichlorophenyl)thien-2-yl}phenoxy)propyl methanesulphonate

Suppliers and Price of 3-(4-{5-[(4-Carbamoyl-4-phenylpiperidin-1-yl) carbonyl]-3-(2,4-dichlorophenyl)thien-2-yl}phenoxy)propyl methanesulphonate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 3-(4-{5-[(4-Carbamoyl-4-phenylpiperidin-1-yl) carbonyl]-3-(2,4-dichlorophenyl)thien-2-yl}phenoxy)propyl methanesulphonate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 3-(4-{5-[(4-Carbamoyl-4-phenylpiperidin-1-yl) carbonyl]-3-(2,4-dichlorophenyl)thien-2-yl}phenoxy)propyl methanesulphonate

There total 5 articles about 3-(4-{5-[(4-Carbamoyl-4-phenylpiperidin-1-yl) carbonyl]-3-(2,4-dichlorophenyl)thien-2-yl}phenoxy)propyl methanesulphonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1207202-75-2
1-({4-(2,4-Dichlorophenyl)-5-[4-(3-hydroxypropoxy)phenyl]thien-2-yl}carbonyl)-4-phenylpiperidine-4-carboxamide

: 124-63-0
methanesulfonyl chloride

: 1207203-51-7
3-(4-{5-[(4-Carbamoyl-4-phenylpiperidin-1-yl) carbonyl]-3-(2,4-dichlorophenyl)thien-2-yl}phenoxy)propyl methanesulphonate

Guidance literature:: With triethylamine; In dichloromethane; at 20 ℃; for 1h;

Reference yield:

: 80139-80-6
4-carbamoyl-4-phenylpiperidine

: 1207203-51-7
3-(4-{5-[(4-Carbamoyl-4-phenylpiperidin-1-yl) carbonyl]-3-(2,4-dichlorophenyl)thien-2-yl}phenoxy)propyl methanesulphonate

Guidance literature:: Multi-step reaction with 4 steps

1: triethylamine; O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate / dichloromethane / 20 °C

2: boron tribromide / dichloromethane / 20 °C / Cooling with ice

3: potassium carbonate / N,N-dimethyl-formamide / 3 h / 110 °C

4: triethylamine / dichloromethane / 1 h / 20 °C

With boron tribromide; potassium carbonate; O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; triethylamine; In dichloromethane; N,N-dimethyl-formamide;

Reference yield:

: 1207203-47-1
4-(2,4-dichlorophenyl)-5-(4-methoxyphenyl)thiophene-2-carboxylic acid

: 1207203-51-7
3-(4-{5-[(4-Carbamoyl-4-phenylpiperidin-1-yl) carbonyl]-3-(2,4-dichlorophenyl)thien-2-yl}phenoxy)propyl methanesulphonate

Guidance literature:: Multi-step reaction with 4 steps

1: triethylamine; O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate / dichloromethane / 20 °C

2: boron tribromide / dichloromethane / 20 °C / Cooling with ice

3: potassium carbonate / N,N-dimethyl-formamide / 3 h / 110 °C

4: triethylamine / dichloromethane / 1 h / 20 °C

With boron tribromide; potassium carbonate; O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; triethylamine; In dichloromethane; N,N-dimethyl-formamide;