Welcome to LookChem.com Sign In|Join Free
  • or

Encyclopedia

1-methylindole-5-carboxylic Acid

Base Information Edit
  • Chemical Name:1-methylindole-5-carboxylic Acid
  • CAS No.:186129-25-9
  • Molecular Formula:C10H9NO2
  • Molecular Weight:175.187
  • Hs Code.:2933998090
  • European Community (EC) Number:676-097-4
  • DSSTox Substance ID:DTXSID20426748
  • Wikidata:Q72491940
  • Mol file:186129-25-9.mol
1-methylindole-5-carboxylic Acid

Synonyms:1-Methyl-1H-Indole-5-Carboxylic Acid;186129-25-9;1-methylindole-5-carboxylic Acid;1-Methyl-5-indolecarboxylic Acid;1H-Indole-5-carboxylic acid, 1-methyl-;MFCD03839859;1-Methyl-5-indolecarboxylicAcid;SCHEMBL103922;N-methylindol-5-carboxylic acid;DTXSID20426748;UHQAIJFIXCOBCN-UHFFFAOYSA-N;Methyl 1H-indole-5-carboxylic acid;BBL010464;STK719877;1-methyl-1H-indol-5-carboxylic acid;AKOS005174503;AB92306;FS-2252;AM803416;SY022474;A4116;BB 0259462;CS-0073862;FT-0647909;1-methylindole-5-carboxylic acid, AldrichCPR;EN300-186478;Q-102905;F2173-1246;Z1154255784;1-methyl-1H-indole-5-carboxylic acid

Suppliers and Price of 1-methylindole-5-carboxylic Acid
Supply Marketing:Edit
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • TRC
  • 5-Carboxy-1-methylindole
  • 50mg
  • $ 45.00
  • TRC
  • 5-Carboxy-1-methylindole
  • 500mg
  • $ 75.00
  • SynQuest Laboratories
  • 1-Methyl-1H-indole-5-carboxylic acid 97%
  • 1 g
  • $ 109.00
  • Crysdot
  • 1-Methyl-1H-indole-5-carboxylicacid 97%
  • 100g
  • $ 585.00
  • Chemenu
  • 1-methyl-1H-indole-5-carboxylicacid 95%+
  • 100g
  • $ 553.00
  • AstaTech
  • 1-METHYLINDOLE-5-CARBOXYLICACID 96%
  • 5 / G
  • $ 75.00
  • AstaTech
  • 1-METHYLINDOLE-5-CARBOXYLICACID 96%
  • 25 / G
  • $ 372.00
  • Apolloscientific
  • 1-Methyl-1H-indole-5-carboxylicacid 97%
  • 1g
  • $ 99.00
  • Apolloscientific
  • 1-Methyl-1H-indole-5-carboxylicacid 97%
  • 250mg
  • $ 54.00
  • AOBChem
  • 1-Methyl-1H-indole-5-carboxylicacid 97%
  • 100g
  • $ 1260.00
Total 29 raw suppliers
Chemical Property of 1-methylindole-5-carboxylic Acid Edit
Chemical Property:
  • Vapor Pressure:9.54E-07mmHg at 25°C 
  • Melting Point:221-223.5 °C 
  • Refractive Index:1.612 
  • Boiling Point:389 °C at 760 mmHg 
  • PKA:4.44±0.30(Predicted) 
  • Flash Point:189 °C 
  • PSA:42.23000 
  • Density:1.24 g/cm3 
  • LogP:1.87650 
  • Storage Temp.:2-8°C 
  • XLogP3:2.2
  • Hydrogen Bond Donor Count:1
  • Hydrogen Bond Acceptor Count:2
  • Rotatable Bond Count:1
  • Exact Mass:175.063328530
  • Heavy Atom Count:13
  • Complexity:217
Purity/Quality:

98%min *data from raw suppliers

5-Carboxy-1-methylindole *data from reagent suppliers

Safty Information:
  • Pictogram(s): R36/37/38:; 
  • Hazard Codes:Xn,Xi 
  • Statements: 36/37/38-20/21/22-36 
  • Safety Statements: 26-36/37/39-22 
MSDS Files:

SDS file from LookChem

Useful:
  • Canonical SMILES:CN1C=CC2=C1C=CC(=C2)C(=O)O
  • Uses 5-Carboxy-1-methylindole is used in the preparation of diazaspiro ROCK inhibitors which is used for treating diseases.
Technology Process of 1-methylindole-5-carboxylic Acid

There total 14 articles about 1-methylindole-5-carboxylic Acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:
Guidance literature:
With water; sodium hydroxide; In tetrahydrofuran; at 40 ℃; for 4h;
Guidance literature:
1H-Indole-5-carboxylic acid; With sodium hydride; In N,N-dimethyl-formamide; at 0 ℃; for 0.5h;
methyl iodide; In N,N-dimethyl-formamide; at 20 ℃; for 12h;
DOI:10.1016/j.ejmech.2019.01.066
Post RFQ for Price