C₁₅H₉ClF₃NO₂

Base Information

• Chemical Name: C₁₅H₉ClF₃NO₂
• CAS No.: 1413930-09-2
• Molecular Formula: C₁₅H₉ClF₃NO₂
• Molecular Weight: 327.69
• Mol file: 1413930-09-2.mol

Synonyms:C₁₅H₉ClF₃NO₂

Chemical Property of C₁₅H₉ClF₃NO₂

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of C₁₅H₉ClF₃NO₂

There total 5 articles about C₁₅H₉ClF₃NO₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 49.0%

C15H11ClF3NO3 (1413929-76-6) → C15H11ClF3NO2S (1413929-93-7) + C15H9ClF3NO2 (1413930-09-2)

Guidance literature:

C₁₅H₁₁ClF₃NO₃; With pyridine; tetraphosphorus decasulfide; at 155 ℃; for 4h; Reflux;

With hydrogenchloride; In chloroform; water; at 110 ℃; for 1h; Reflux;

DOI:10.1016/j.ejmech.2012.08.016

Reference yield:

5-chloro-2-methoxybenzoic acid (3438-16-2) → C15H11ClF3NO2S (1413929-93-7) + C15H9ClF3NO2 (1413930-09-2)

Guidance literature:

Multi-step reaction with 3 steps

1.1: thionyl chloride / 3 h / Reflux

2.1: triethylamine / diethyl ether / 1 h / 20 °C

3.1: pyridine; tetraphosphorus decasulfide / 4 h / 155 °C / Reflux

3.2: 1 h / 110 °C / Reflux

With pyridine; thionyl chloride; tetraphosphorus decasulfide; triethylamine; In diethyl ether;

DOI:10.1016/j.ejmech.2012.08.016

Reference yield:

3-Trifluoromethylphenol (98-17-9) → C15H11ClF3NO2S (1413929-93-7) + C15H9ClF3NO2 (1413930-09-2)

Guidance literature:

Multi-step reaction with 4 steps

1.1: acetic acid; nitric acid / 1 h / 20 - 40 °C

2.1: acetic acid; iron / water / 0.75 h / 135 °C

3.1: triethylamine / diethyl ether / 1 h / 20 °C

4.1: pyridine; tetraphosphorus decasulfide / 4 h / 155 °C / Reflux

4.2: 1 h / 110 °C / Reflux

With pyridine; tetraphosphorus decasulfide; nitric acid; iron; acetic acid; triethylamine; In diethyl ether; water;

DOI:10.1016/j.ejmech.2012.08.016

upstream raw materials:

C₁₅H₁₁ClF₃NO₃

2-nitro-5-trifluoromethylphenol

2-hydroxy-4-(trifluoromethyl)aniline

2-methoxy-5-chlorobenzoyl chloride