1-Cyclohexylpiperidin-4-one

Base Information

Chemical Name:1-Cyclohexylpiperidin-4-one
CAS No.:16771-84-9
Molecular Formula:C11H19NO
Molecular Weight:181.278
Hs Code.:2933399090
European Community (EC) Number:803-248-5
DSSTox Substance ID:DTXSID60482520
Wikidata:Q82318928
Mol file:16771-84-9.mol

Synonyms:1-cyclohexylpiperidin-4-one;16771-84-9;1-Cyclohexyl-4-piperidinone;1-cyclohexyltetrahydro-4(1H)-pyridinone;4-Piperidinone,1-cyclohexyl-;N-Cyclohexyl-4-Piperidone;4-Piperidinone, 1-cyclohexyl-;SCHEMBL1181799;DTXSID60482520;QQYHUQVNANUTNM-UHFFFAOYSA-N;MFCD03840833;AKOS000179104;AB16700;LA-0801;1-cyclohexyl-4-piperidinone, AldrichCPR;AC-12614;CS-0216624;FT-0681174;EN300-52938;E10274;J-504550;Z295882146

Suppliers and Price of 1-Cyclohexylpiperidin-4-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
1-Cyclohexylpiperidin-4-one
50mg
$ 45.00

Matrix Scientific
1-Cyclohexyltetrahydro-4(1H)-pyridinone >95%
1g
$ 228.00

Matrix Scientific
1-Cyclohexyltetrahydro-4(1H)-pyridinone >95%
5g
$ 524.00

Crysdot
1-Cyclohexylpiperidin-4-one 95+%
5g
$ 506.00

Chemenu
1-Cyclohexylpiperidin-4-one 95%
5g
$ 473.00

American Custom Chemicals Corporation
1-CYCLOHEXYL-4-PIPERIDINONE 95.00%
1G
$ 852.55

American Custom Chemicals Corporation
1-CYCLOHEXYL-4-PIPERIDINONE 95.00%
5G
$ 1548.26

American Custom Chemicals Corporation
1-CYCLOHEXYL-4-PIPERIDINONE 95.00%
2.5G
$ 1227.82

AK Scientific
1-Cyclohexyl-4-piperidinone
5g
$ 923.00

AK Scientific
1-Cyclohexyl-4-piperidinone
250mg
$ 227.00

Total 18 raw suppliers

Chemical Property of 1-Cyclohexylpiperidin-4-one

Chemical Property:

Vapor Pressure:0.00193mmHg at 25°C
Refractive Index:1.4959 (20℃)
Boiling Point:291.6 °C at 760 mmHg
Flash Point:121.6 °C
PSA：20.31000
Density:1.041g/cm³
LogP:1.92190
XLogP3:1.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:181.146664230
Heavy Atom Count:13
Complexity:175

Purity/Quality:

97% ^*data from raw suppliers

1-Cyclohexylpiperidin-4-one ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 37/38-41
Safety Statements: 26-39

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CCC(CC1)N2CCC(=O)CC2

Technology Process of 1-Cyclohexylpiperidin-4-one

There total 5 articles about 1-Cyclohexylpiperidin-4-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

: 3592-25-4
1,5-dichloropentan-3-one

: 108-91-8,157973-60-9
cyclohexylamine

: 16771-84-9
1-cyclohexyl-4-piperidinone

Guidance literature:: With sodium carbonate; In methanol; for 1.5h; Heating;
DOI:10.1002/recl.19931121005

Reference yield:

: 1225486-33-8
C₁₃H₂₁NO₃

: 16771-84-9
1-cyclohexyl-4-piperidinone

Guidance literature:: C₁₃H₂₁NO₃; With hydrogenchloride; In water; Reflux;

With sodium hydroxide; at 20 ℃;
DOI:10.1002/jhet.916

Reference yield:

: 108-91-8,157973-60-9
cyclohexylamine

: 16771-84-9
1-cyclohexyl-4-piperidinone

Guidance literature:: Multi-step reaction with 3 steps

1.1: acetic acid / methanol / Reflux

2.1: sodium; methanol / toluene / Reflux

3.1: hydrogenchloride / water / Reflux

3.2: 20 °C

With hydrogenchloride; methanol; sodium; acetic acid; In methanol; water; toluene; 1.1: |Michael Addition / 2.1: |Dieckmann Condensation;
DOI:10.1002/jhet.916