Toluene-4-sulfonic acid (2R,3R)-3-azido-2-hydroxy-3-phenyl-propyl ester

Base Information

Chemical Name:Toluene-4-sulfonic acid (2R,3R)-3-azido-2-hydroxy-3-phenyl-propyl ester
CAS No.:156350-20-8
Molecular Formula:C₁₆H₁₇N₃O₄S
Molecular Weight:347.395
Hs Code.:

Synonyms:Toluene-4-sulfonic acid (2R,3R)-3-azido-2-hydroxy-3-phenyl-propyl ester

Suppliers and Price of Toluene-4-sulfonic acid (2R,3R)-3-azido-2-hydroxy-3-phenyl-propyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Toluene-4-sulfonic acid (2R,3R)-3-azido-2-hydroxy-3-phenyl-propyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Toluene-4-sulfonic acid (2R,3R)-3-azido-2-hydroxy-3-phenyl-propyl ester

There total 1 articles about Toluene-4-sulfonic acid (2R,3R)-3-azido-2-hydroxy-3-phenyl-propyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 121745-57-1
(2R,3R)-3-azido-3-phenyl-propane-1,2diol

: 98-59-9
p-toluenesulfonyl chloride

: 156350-20-8
Toluene-4-sulfonic acid (2R,3R)-3-azido-2-hydroxy-3-phenyl-propyl ester

Guidance literature:: With triethylamine; In dichloromethane; for 4h; Ambient temperature;
DOI:10.1016/S0040-4039(00)74779-4

Reference yield:

: 156350-20-8
Toluene-4-sulfonic acid (2R,3R)-3-azido-2-hydroxy-3-phenyl-propyl ester

: 146499-49-2
(2R,3S)-N-p-toluenesulfonyl-3-tert-butyldimethylsiloxy-2-phenylazetidine

Guidance literature:: Multi-step reaction with 5 steps

1: imidazole / dimethylformamide / 19 h / Ambient temperature

2: 1.33 g / 5percent Pd-C, HCO₂NH₄ / methanol / 1 h / Ambient temperature

3: Et₃N, DMAP / CH₂Cl₂ / 3 h / Ambient temperature

4: 18 percent / NaH / methanol / 11 h / Ambient temperature

5: 99 percent / imidazole / dimethylformamide / 3 h / 50 °C

With 1H-imidazole; dmap; palladium on activated charcoal; ammonium formate; sodium hydride; triethylamine; In methanol; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1016/S0040-4020(01)80749-3

Reference yield:

: 156350-20-8
Toluene-4-sulfonic acid (2R,3R)-3-azido-2-hydroxy-3-phenyl-propyl ester

: 146499-48-1
(2R,3R)-2-tert-butyldimethylsiloxy-3-phenyl-3-p-toluenesulfonylamino-1-p-toluenesulfonylpropane

Guidance literature:: Multi-step reaction with 3 steps

1: imidazole / dimethylformamide / 19 h / Ambient temperature

2: 1.33 g / 5percent Pd-C, HCO₂NH₄ / methanol / 1 h / Ambient temperature

3: Et₃N, DMAP / CH₂Cl₂ / 3 h / Ambient temperature

With 1H-imidazole; dmap; palladium on activated charcoal; ammonium formate; triethylamine; In methanol; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1016/S0040-4020(01)80749-3