(E)-1-(1-benzyl-5-methyl-1H-1,2,3-triazol-4-yl)-3-(2,4-dichlorophenyl)prop-2-en-1-one

Base Information

• Chemical Name: (E)-1-(1-benzyl-5-methyl-1H-1,2,3-triazol-4-yl)-3-(2,4-dichlorophenyl)prop-2-en-1-one
• CAS No.: 1403580-83-5
• Molecular Formula: C₁₉H₁₅Cl₂N₃O
• Molecular Weight: 372.254
• Mol file: 1403580-83-5.mol

Synonyms:(E)-1-(1-benzyl-5-methyl-1H-1,2,3-triazol-4-yl)-3-(2,4-dichlorophenyl)prop-2-en-1-one

Chemical Property of (E)-1-(1-benzyl-5-methyl-1H-1,2,3-triazol-4-yl)-3-(2,4-dichlorophenyl)prop-2-en-1-one

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (E)-1-(1-benzyl-5-methyl-1H-1,2,3-triazol-4-yl)-3-(2,4-dichlorophenyl)prop-2-en-1-one

There total 4 articles about (E)-1-(1-benzyl-5-methyl-1H-1,2,3-triazol-4-yl)-3-(2,4-dichlorophenyl)prop-2-en-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

1-(1-benzyl-5-methyl-1H-1,2,3-triazol-4-yl)ethan-1-one (133992-60-6) + 2,4-dichlorobenzaldeyhde (874-42-0) → (E)-1-(1-benzyl-5-methyl-1H-1,2,3-triazol-4-yl)-3-(2,4-dichlorophenyl)prop-2-en-1-one (1403580-83-5)

Guidance literature:

With sodium hydroxide; In water; at 20 ℃; for 0.116667h;

DOI:10.1007/s12039-012-0281-x

Reference yield:

acetylacetone (123-54-6,81235-32-7) → (E)-1-(1-benzyl-5-methyl-1H-1,2,3-triazol-4-yl)-3-(2,4-dichlorophenyl)prop-2-en-1-one (1403580-83-5)

Guidance literature:

Multi-step reaction with 2 steps

1: potassium carbonate / ethanol / 0.5 h / 75 °C

2: sodium hydroxide / water / 0.12 h / 20 °C

With potassium carbonate; sodium hydroxide; In ethanol; water;

DOI:10.1007/s12039-012-0281-x

Reference yield:

benzyl azide (622-79-7) → (E)-1-(1-benzyl-5-methyl-1H-1,2,3-triazol-4-yl)-3-(2,4-dichlorophenyl)prop-2-en-1-one (1403580-83-5)

Guidance literature:

Multi-step reaction with 2 steps

1: potassium carbonate / ethanol / 0.5 h / 75 °C

2: sodium hydroxide / water / 0.12 h / 20 °C

With potassium carbonate; sodium hydroxide; In ethanol; water;

DOI:10.1007/s12039-012-0281-x

upstream raw materials:

1-(1-benzyl-5-methyl-1H-1,2,3-triazol-4-yl)ethan-1-one

2,4-dichlorobenzaldeyhde

benzyl azide

acetylacetone

Downstream raw materials:

C₂₇H₂₂Cl₂N₄O

C₂₈H₂₄Cl₂N₄O

4-(1-benzyl-5-methyl-1H-1,2,3-triazol-4-yl)-6-(2,4-dichlorophenyl)pyrimidin-2-amine

C₂₀H₁₇Cl₂N₅S