C₁₉H₁₇BrF₄N₂O₇S

Base Information

Chemical Name:C₁₉H₁₇BrF₄N₂O₇S
CAS No.:1386985-98-3
Molecular Formula:C₁₉H₁₇BrF₄N₂O₇S
Molecular Weight:573.317
Hs Code.:

C<sub>19</sub>H<sub>17</sub>BrF<sub>4</sub>N<sub>2</sub>O<sub>7</sub>S

Synonyms:C₁₉H₁₇BrF₄N₂O₇S

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Chemical Property of C₁₉H₁₇BrF₄N₂O₇S

Chemical Property:

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Technology Process of C₁₉H₁₇BrF₄N₂O₇S

There total 3 articles about C₁₉H₁₇BrF₄N₂O₇S which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1386985-96-1
2-[(R)-2-(5-bromo-2-fluoro-phenyl)-3-fluoro-2-(2-nitro-benzenesulfonylamino)-propoxy]-3-fluoro-2-fluoromethyl-propionic acid ethyl ester

: 1386985-98-3
C₁₉H₁₇BrF₄N₂O₇S

Guidance literature:: 2-[(R)-2-(5-bromo-2-fluoro-phenyl)-3-fluoro-2-(2-nitro-benzenesulfonylamino)-propoxy]-3-fluoro-2-fluoromethyl-propionic acid ethyl ester; With water; lithium hydroxide; In tetrahydrofuran; methanol; at 20 ℃; for 0.5h;

With hydrogenchloride; In tetrahydrofuran; methanol; water; ethyl acetate;

Reference yield:

: C₂₀H₂₁BrF₂N₂O₆S

: 1386985-98-3
C₁₉H₁₇BrF₄N₂O₇S

Guidance literature:: Multi-step reaction with 4 steps

1.1: camphor-10-sulfonic acid; methanol / tetrahydrofuran / 6 h

2.1: triphenylphosphine; diethylazodicarboxylate / toluene; tetrahydrofuran / 2.5 h / 0 - 20 °C

3.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 0.5 h / 20 °C / Inert atmosphere

3.2: 16 h / 25 °C / Inert atmosphere

4.1: water; lithium hydroxide / tetrahydrofuran; methanol / 0.5 h / 20 °C

With methanol; camphor-10-sulfonic acid; water; sodium hydride; triphenylphosphine; lithium hydroxide; diethylazodicarboxylate; In tetrahydrofuran; methanol; N,N-dimethyl-formamide; toluene; mineral oil;

Reference yield:

: 1386985-95-0
(R)-2-(5-bromo-2-fluoro-phenyl)-2-fluoromethyl-1-(2-nitro-benzenesulfonyl)-aziridine

: 1386985-98-3
C₁₉H₁₇BrF₄N₂O₇S

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 0.5 h / 20 °C / Inert atmosphere

1.2: 16 h / 25 °C / Inert atmosphere

2.1: water; lithium hydroxide / tetrahydrofuran; methanol / 0.5 h / 20 °C

With water; sodium hydride; lithium hydroxide; In tetrahydrofuran; methanol; N,N-dimethyl-formamide; mineral oil;