tert-Butoxychlorodiphenylsilane

Base Information

• Chemical Name: tert-Butoxychlorodiphenylsilane
• CAS No.: 17922-24-6
• Molecular Formula: C16H19ClOSi
• Molecular Weight: 290.865
• Hs Code.: 29319090
• European Community (EC) Number: 626-967-4
• DSSTox Substance ID: DTXSID60370857
• Nikkaji Number: J254.909C
• Wikidata: Q82158012
• Mol file: 17922-24-6.mol

Synonyms:tert-Butoxychlorodiphenylsilane;17922-24-6;tert-Butoxy(chloro)diphenylsilane;chloro-[(2-methylpropan-2-yl)oxy]-diphenylsilane;tert-Butoxydiphenylchlorosilane;Benzene, 1,1'-[chloro(1,1-dimethylethoxy)silylene]bis-;t-butoxydiphenylsilyl chloride;SCHEMBL766008;Benzene,1,1'-[chloro(1,1-dimethylethoxy)silylene]bis-;tert-Butoxydiphenylsilyl Chloride;DTXSID60370857;BBL102587;MFCD00077672;STL556390;AKOS005255036;FS-3988;B1436;FT-0637626;T70450;A812436;J-011434;tert-Butoxy(chloro)diphenylsilane, >=97.0% (GC);chloranyl-[(2-methylpropan-2-yl)oxy]-diphenyl-silane;TERT-BUTOXYDIPHENYLCHLOROSILANE (STABILIZED WITH CACO3)

Chemical Property of tert-Butoxychlorodiphenylsilane

Chemical Property:

• Refractive Index: n20/D 1.539
• Boiling Point: 331 °C at 760 mmHg
• Flash Point: 128.2 °C
• PSA: 9.23000
• Density: 1.07 g/cm³
• LogP: 3.29690
• Storage Temp.: −20°C
• Sensitive.: Moisture Sensitive
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 4
• Exact Mass: 290.0893695
• Heavy Atom Count: 19
• Complexity: 257

Purity/Quality:

98% ^*data from raw suppliers

tert-Butoxydiphenylchlorosilane ^*data from reagent suppliers

Safty Information:

• Pictogram(s): C
• Hazard Codes: C
• Statements: 34
• Safety Statements: 26-36/37/39-45

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C)(C)O[Si](C1=CC=CC=C1)(C2=CC=CC=C2)Cl

Technology Process of tert-Butoxychlorodiphenylsilane

There total 1 articles about tert-Butoxychlorodiphenylsilane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

diphenylsilyl dichloride (80-10-4) + tert-butyl alcohol (75-65-0) → tert-butyloxydiphenylsilyl chloride (17922-24-6)

Guidance literature:

With triethylamine; In dichloromethane; at 20 ℃; for 32h; Inert atmosphere; Reflux;

DOI:10.1021/acs.orglett.5b03008

Reference yield: 100.0%

tert-butyloxydiphenylsilyl chloride (17922-24-6) + (2R,3R,4R)-2,4-dimethyl-5-(phenylthio)pentane-1,3-diol (177568-10-4) → (2R,3R,4R)-1-tert-butyl-diphenylsilyloxy-2,4-dimethyl-5-(phenylthio)pentan-3-ol

Guidance literature:

tert-butyloxydiphenylsilyl chloride; With 1H-imidazole; In N,N-dimethyl-formamide; at 20 ℃; for 0.5h; Inert atmosphere;

(2R,3R,4R)-2,4-dimethyl-5-(phenylthio)pentane-1,3-diol; In N,N-dimethyl-formamide; at 20 ℃; for 14h; Inert atmosphere;

DOI:10.1246/bcsj.20140271

Reference yield: 99.0%

4-{(2R,6S)-6-[(R)-3-(4-Methoxy-benzyloxy)-2-methyl-propyl]-5,6-dihydro-2H-pyran-2-yl}-but-2-yn-1-ol (856410-65-6) + tert-butyloxydiphenylsilyl chloride (17922-24-6) → tert-butoxy-(4-{6-[3-(4-methoxy-benzyloxy)-2-methyl-propyl]-5,6-dihydro-2H-pyran-2-yl}-but-2-ynyloxy)-diphenyl-silane (856410-46-3)

Guidance literature:

With triethylamine; In dichloromethane; at 20 ℃;

DOI:10.1002/anie.200500029

upstream raw materials:

diphenylsilyl dichloride

tert-butyl alcohol

Downstream raw materials:

2-octyl-tert-butoxydiphenylsilyl ether

3-(tert-Butoxy-diphenyl-silanyloxymethyl)-heptan-4-ol

tert-Butoxy-dodecyloxy-diphenyl-silane

1-methylcyclohexyl tert-butoxydiphenylsilyl ether

Refernces

• 1、 Kojima, Satoshi,Fukuzaki, Tomohide,Yamakawa, Atsushi,Murai, Yutaka. "Highly (Z)-selective synthesis of β-monosubstituted α,β-unsaturated cyanides using the peterson reaction". . p. 3917 - 3920. Retrieved 2007/10/03.