propyl {(7R)-7-{[(4-fluorophenyl)sulfonyl]amino}-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl}acetate

Base Information

Chemical Name:propyl {(7R)-7-{[(4-fluorophenyl)sulfonyl]amino}-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl}acetate
CAS No.:1218918-74-1
Molecular Formula:C₂₃H₂₅FN₂O₄S
Molecular Weight:444.527
Hs Code.:

Synonyms:propyl {(7R)-7-{[(4-fluorophenyl)sulfonyl]amino}-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl}acetate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of propyl {(7R)-7-{[(4-fluorophenyl)sulfonyl]amino}-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl}acetate

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Technology Process of propyl {(7R)-7-{[(4-fluorophenyl)sulfonyl]amino}-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl}acetate

There total 1 articles about propyl {(7R)-7-{[(4-fluorophenyl)sulfonyl]amino}-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl}acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1218918-73-0
propyl ((7R)-7-amino-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl)acetate

: 349-88-2
4-Fluorobenzenesulfonyl chloride

: 1218918-74-1
propyl {(7R)-7-{[(4-fluorophenyl)sulfonyl]amino}-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl}acetate

Guidance literature:: With triethylamine; In dichloromethane; at 20 ℃; for 12h;

Reference yield: 98.0%

: 1218918-74-1
propyl {(7R)-7-{[(4-fluorophenyl)sulfonyl]amino}-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl}acetate

: 74-88-4
methyl iodide

: 1218918-75-2
propyl {(7R)-7-{[(4-fluorophenyl)sulfonyl](methyl)amino}-6,7,8,9-tetrahydro-pyrido[1,2-a]indol-10-yl}acetate

Guidance literature:: propyl {(7R)-7-{[(4-fluorophenyl)sulfonyl]amino}-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl}acetate; With sodium hydride; In N,N-dimethyl-formamide; at 0 ℃; for 0.5h;

methyl iodide; In N,N-dimethyl-formamide; at 0 ℃; for 2h;