Phenyl-(2,8,9-trioxa-1λ⁵-phospha-tricyclo[3.3.1.1^3,7]dec-1-ylidene)-amine

Base Information

• Chemical Name: Phenyl-(2,8,9-trioxa-1λ⁵-phospha-tricyclo[3.3.1.1^3,7]dec-1-ylidene)-amine
• CAS No.: 75543-69-0
• Molecular Formula: C₁₂H₁₄NO₃P
• Molecular Weight: 251.222
• Mol file: 75543-69-0.mol

Synonyms:Phenyl-(2,8,9-trioxa-1λ⁵-phospha-tricyclo[3.3.1.1^3,7]dec-1-ylidene)-amine

Chemical Property of Phenyl-(2,8,9-trioxa-1λ⁵-phospha-tricyclo[3.3.1.1^3,7]dec-1-ylidene)-amine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Phenyl-(2,8,9-trioxa-1λ⁵-phospha-tricyclo[3.3.1.1^3,7]dec-1-ylidene)-amine

There total 2 articles about Phenyl-(2,8,9-trioxa-1λ⁵-phospha-tricyclo[3.3.1.1^3,7]dec-1-ylidene)-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

2,8,9-trioxa-1-phospha-adamantane (281-33-4) + Phenyl azide (622-37-7) → Phenyl-(2,8,9-trioxa-1λ5-phospha-tricyclo[3.3.1.13,7]dec-1-ylidene)-amine (75543-69-0)

Guidance literature:

In chloroform; at 0 ℃; for 3.5h;

Reference yield:

1,3,5-cyclohexanetriol (2041-15-8,13314-30-2) → Phenyl-(2,8,9-trioxa-1λ5-phospha-tricyclo[3.3.1.13,7]dec-1-ylidene)-amine (75543-69-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 90 percent / triethyl phosphite / 18 h / 110 °C

2: 75 percent / CHCl₃ / 3.5 h / 0 °C

With triethyl phosphite; In chloroform;

Reference yield:

Phenyl-(2,8,9-trioxa-1λ5-phospha-tricyclo[3.3.1.13,7]dec-1-ylidene)-amine (75543-69-0) + ethylene glycol (107-21-1) → α-Cyclohexantriol-(1a,3a,5a)-phosphat (875-12-7) + C8H13O5P (34442-16-5)

Guidance literature:

In chloroform; at -70 ℃; Title compound not separated from byproducts;

upstream raw materials:

2,8,9-trioxa-1-phospha-adamantane

Phenyl azide

1,3,5-cyclohexanetriol

Downstream raw materials:

α-Cyclohexantriol-(1a,3a,5a)-phosphat

C₈H₁₃O₅P