3-benzyl-1-(2-ethoxy-2-oxoethyl)-4,5-bis(methoxycarbonyl)-1H-imidazol-3-ium tetrafluoroborate

Base Information

• Chemical Name: 3-benzyl-1-(2-ethoxy-2-oxoethyl)-4,5-bis(methoxycarbonyl)-1H-imidazol-3-ium tetrafluoroborate
• CAS No.: 1462886-23-2
• Molecular Formula: BF₄*C₁₈H₂₁N₂O₆
• Molecular Weight: 448.179
• Mol file: 1462886-23-2.mol

Synonyms:3-benzyl-1-(2-ethoxy-2-oxoethyl)-4,5-bis(methoxycarbonyl)-1H-imidazol-3-ium tetrafluoroborate

Chemical Property of 3-benzyl-1-(2-ethoxy-2-oxoethyl)-4,5-bis(methoxycarbonyl)-1H-imidazol-3-ium tetrafluoroborate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-benzyl-1-(2-ethoxy-2-oxoethyl)-4,5-bis(methoxycarbonyl)-1H-imidazol-3-ium tetrafluoroborate

There total 4 articles about 3-benzyl-1-(2-ethoxy-2-oxoethyl)-4,5-bis(methoxycarbonyl)-1H-imidazol-3-ium tetrafluoroborate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

sodium tetrafluoroborate (13755-29-8) + 3-benzyl-1-(2-ethoxy-2-oxoethyl)-4,5-bis(methoxycarbonyl)-1H-imidazol-3-ium bromide (1462886-21-0) → 3-benzyl-1-(2-ethoxy-2-oxoethyl)-4,5-bis(methoxycarbonyl)-1H-imidazol-3-ium tetrafluoroborate (1462886-23-2)

Guidance literature:

In acetone; at 20 ℃; for 96h; Inert atmosphere;

DOI:10.1039/c3gc40975a

Reference yield:

dimethyl imidazole-4,5-dicarboxylate (3304-70-9) → 3-benzyl-1-(2-ethoxy-2-oxoethyl)-4,5-bis(methoxycarbonyl)-1H-imidazol-3-ium tetrafluoroborate (1462886-23-2)

Guidance literature:

Multi-step reaction with 3 steps

1: potassium carbonate / acetonitrile / 48 h / 20 °C / Inert atmosphere

2: acetonitrile / 72 h / 20 °C

3: acetone / 96 h / 20 °C / Inert atmosphere

With potassium carbonate; In acetone; acetonitrile;

DOI:10.1039/c3gc40975a

Reference yield:

4,5-imidazoledicarboxylic acid (570-22-9) → 3-benzyl-1-(2-ethoxy-2-oxoethyl)-4,5-bis(methoxycarbonyl)-1H-imidazol-3-ium tetrafluoroborate (1462886-23-2)

Guidance literature:

Multi-step reaction with 4 steps

1: sulfuric acid / 24 h / Reflux

2: potassium carbonate / acetonitrile / 48 h / 20 °C / Inert atmosphere

3: acetonitrile / 72 h / 20 °C

4: acetone / 96 h / 20 °C / Inert atmosphere

With sulfuric acid; potassium carbonate; In acetone; acetonitrile;

DOI:10.1039/c3gc40975a

upstream raw materials:

sodium tetrafluoroborate

3-benzyl-1-(2-ethoxy-2-oxoethyl)-4,5-bis(methoxycarbonyl)-1H-imidazol-3-ium bromide

4,5-imidazoledicarboxylic acid

dimethyl imidazole-4,5-dicarboxylate