2,6-bis(2,5-diphenylphospholyl-1-methyl)pyridine

Base Information

• Chemical Name: 2,6-bis(2,5-diphenylphospholyl-1-methyl)pyridine
• CAS No.: 777069-44-0
• Molecular Formula: C₃₉H₃₁NP₂
• Molecular Weight: 575.629
• Mol file: 777069-44-0.mol

Synonyms:2,6-bis(2,5-diphenylphospholyl-1-methyl)pyridine

Chemical Property of 2,6-bis(2,5-diphenylphospholyl-1-methyl)pyridine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,6-bis(2,5-diphenylphospholyl-1-methyl)pyridine

There total 1 articles about 2,6-bis(2,5-diphenylphospholyl-1-methyl)pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

2,6-bis(chloromethyl)pyridine (3099-28-3) + diphenyl-2,5-phospholyl-lithium (115171-91-0) → 2,6-bis(2,5-diphenylphospholyl-1-methyl)pyridine (777069-44-0)

Guidance literature:

In tetrahydrofuran; at 20 ℃; for 0.333333h;

DOI:10.1016/j.jorganchem.2004.06.035

Reference yield: 95.0%

silver tetrafluoroborate (14104-20-2) + dichloro(1,5-cyclooctadiene)palladium(II) (12107-56-1) + 2,6-bis(2,5-diphenylphospholyl-1-methyl)pyridine (777069-44-0) → [Pd(2,6-bis(2,5-diphenylphospholyl-1-methyl)pyridine)Cl][BF4] (777069-46-2)

Guidance literature:

In dichloromethane; byproducts: AgCl, 1,5-cyclooctadiene; (N2 or Ar); ligand added to a soln. of Pd complex at room temp., stirredfor 10 min, AgBF4 added, stirred at room temp. for 1 h; filtered (Celite), evapd., washed with hexanes; elem. anal.;

DOI:10.1016/j.jorganchem.2004.06.035

Reference yield: 95.0%

nickel(II) bromide dimethoxyethane (28923-39-9) + silver tetrafluoroborate (14104-20-2) + 2,6-bis(2,5-diphenylphospholyl-1-methyl)pyridine (777069-44-0) → [Ni(2,6-bis(2,5-diphenylphospholyl-1-methyl)pyridine)Br][BF4] (777069-48-4)

Guidance literature:

In dichloromethane; acetonitrile; (N2 or Ar); ligand added to a mixt. of Ni complex in CH2Cl2/MeCN at roomtemp., stirred for 10 min, AgBF4 added, stirred at room temp. for 1 h; filtered (Celite), evapd., crystd. in CH2Cl2 at room temp.; elem. anal.;

DOI:10.1016/j.jorganchem.2004.06.035

upstream raw materials:

2,6-bis(chloromethyl)pyridine

diphenyl-2,5-phospholyl-lithium

Downstream raw materials:

[Pd(2,6-bis(2,5-diphenylphospholyl-1-methyl)pyridine)Cl][BF₄]

[Ni(2,6-bis(2,5-diphenylphospholyl-1-methyl)pyridine)Br][BF₄]