2-IODO-3-FLUORONITROBENZENE

Base Information

• Chemical Name: 2-IODO-3-FLUORONITROBENZENE
• CAS No.: 122455-36-1
• Molecular Formula: C6H3FINO2
• Molecular Weight: 266.998
• Hs Code.: 2904909090
• Mol file: 122455-36-1.mol

Synonyms:2-Iodo-3-fluoronitrobenzene;1-fluoro-2-iodo-3-nitrobenzene;benzene, 1-fluoro-2-iodo-3-nitro-;

Chemical Property of 2-IODO-3-FLUORONITROBENZENE

Chemical Property:

• Vapor Pressure: 0.006mmHg at 25°C
• Refractive Index: 1.635
• Boiling Point: 283.136 °C at 760 mmHg
• Flash Point: 125.036 °C
• PSA: 45.82000
• Density: 2.093 g/cm³
• LogP: 2.86170
• Storage Temp.: 2-8°C(protect from light)

Purity/Quality:

98%min ^*data from raw suppliers

2-Iodo-3-fluoronitrobenzene ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-IODO-3-FLUORONITROBENZENE

There total 4 articles about 2-IODO-3-FLUORONITROBENZENE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

2-fluoro-6-nitrophenyl trifluoromethanesulfonate (122455-35-0) → 1-Fluoro-3-nitroiodobenzene (122455-36-1)

Guidance literature:

With lithium iodide; In 1-methyl-pyrrolidin-2-one; at 132 ℃;

Reference yield:

deoxygenated ortho-dichlorobenzene + 3-nitro-5-iodoaniline (10394-64-6) → 1-Fluoro-3-nitroiodobenzene (122455-36-1) + 1-fluoro-3-iodo-5-nitrobenzene (3819-88-3)

Guidance literature:

With nitrogen; nitrosonium tetrafluoroborate; In dichloromethane;

Reference yield:

1-methyl-pyrrolidin-2-one (872-50-4,26138-58-9) + 2-fluoro-6-nitrophenyl trifluoromethanesulfonate (122455-35-0) → 1-Fluoro-3-nitroiodobenzene (122455-36-1)

Guidance literature:

With lithium iodide;

upstream raw materials:

3-nitro-5-iodoaniline

1-methyl-pyrrolidin-2-one

2-fluoro-6-nitrophenyl trifluoromethanesulfonate

3-fluoro-1-nitrobenzene

Downstream raw materials:

2-Iodo-3-fluoroaniline hydrochloride

3-fluoro-2-iodoaniline

Refernces

• 1、 -. "Compounds and Uses Thereof". Page/Page column 98-99. . Retrieved 2008/06/13.
• 2、 -. "STEROID RECEPTOR MODULATOR COMPOUNDS AND METHODS". . . Retrieved 2008/06/13.