2-Chloro-3-fluorobenzaldehyde

Base Information

Chemical Name:2-Chloro-3-fluorobenzaldehyde
CAS No.:96516-31-3
Molecular Formula:C7H4ClFO
Molecular Weight:158.56
Hs Code.:2913000090
European Community (EC) Number:872-610-2
DSSTox Substance ID:DTXSID00565846
Wikidata:Q72450484
Mol file:96516-31-3.mol

Synonyms:2-Chloro-3-fluorobenzaldehyde;96516-31-3;Benzaldehyde, 2-chloro-3-fluoro-;2-Chloro-3-fluoro-benzaldehyde;MFCD07782053;starbld0008954;2-chlorofluorobenzaldehyde;3-Fluoro-2-chlorobenzaldehyde;SCHEMBL561472;DTXSID00565846;PIZVRLVKXWEMGO-UHFFFAOYSA-N;CL8262;AKOS005063859;AC-2298;AM62155;CS-W007812;GS-4435;SY030967;EN300-91976;A21248;J-508652;Z1198174775

Suppliers and Price of 2-Chloro-3-fluorobenzaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-Chloro-3-fluorobenzaldehyde
100mg
$ 75.00

Oakwood
2-Chloro-3-fluorobenzaldehyde 98%
1g
$ 19.00

Matrix Scientific
2-Chloro-3-fluorobenzaldehyde 95+%
10g
$ 125.00

Matrix Scientific
2-Chloro-3-fluorobenzaldehyde 95+%
5g
$ 70.00

Matrix Scientific
2-Chloro-3-fluorobenzaldehyde 95+%
1g
$ 25.00

Biosynth Carbosynth
2-Chloro-3-fluorobenzaldehyde
250 g
$ 400.00

Biosynth Carbosynth
2-Chloro-3-fluorobenzaldehyde
100 g
$ 175.00

Biosynth Carbosynth
2-Chloro-3-fluorobenzaldehyde
25 g
$ 50.00

Biosynth Carbosynth
2-Chloro-3-fluorobenzaldehyde
50 g
$ 95.00

Apolloscientific
2-Chloro-3-fluorobenzaldehyde 98%
5g
$ 35.00

Total 57 raw suppliers

Chemical Property of 2-Chloro-3-fluorobenzaldehyde

Chemical Property:

Appearance/Colour:Clear colourless to light yellow liquid
Vapor Pressure:0.187mmHg at 25°C
Melting Point:29-32℃
Refractive Index:1.56
Boiling Point:210.995 °C at 760 mmHg
Flash Point:81.407 °C
PSA：17.07000
Density:1.352 g/cm³
LogP:2.29160
Storage Temp.:under inert gas (nitrogen or Argon) at 2-8°C
Sensitive.:Air Sensitive
XLogP3:2.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:157.9934706
Heavy Atom Count:10
Complexity:129

Purity/Quality:

98% ^*data from raw suppliers

2-Chloro-3-fluorobenzaldehyde ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xn
Hazard Codes:Xn

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=C(C(=C1)F)Cl)C=O

Technology Process of 2-Chloro-3-fluorobenzaldehyde

There total 4 articles about 2-Chloro-3-fluorobenzaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 96516-32-4
(2-chloro-3-fluorophenyl)methanol

: 96516-31-3
2-chloro-3-fluoro-benzaldehyde

Guidance literature:: (2-chloro-3-fluorophenyl)methanol; With oxalyl dichloride; dimethyl sulfoxide; In dichloromethane; at -78 - -40 ℃; for 1h;

With triethylamine; In dichloromethane; at -40 - 20 ℃;
DOI:10.1016/j.bmc.2011.01.065

Reference yield:

: 102940-86-3
3-chloro-3-fluorobenzoic acid

: 96516-31-3
2-chloro-3-fluoro-benzaldehyde

Guidance literature:: Multi-step reaction with 2 steps

1.1: borane-THF / tetrahydrofuran / 0 °C / Reflux

1.2: Cooling with ice

2.1: oxalyl dichloride; dimethyl sulfoxide / dichloromethane / 1 h / -78 - -40 °C

2.2: -40 - 20 °C

With borane-THF; oxalyl dichloride; dimethyl sulfoxide; In tetrahydrofuran; dichloromethane;
DOI:10.1016/j.bmc.2011.01.065