C₃₃H₂₈NO₉P

Base Information

• Chemical Name: C₃₃H₂₈NO₉P
• CAS No.: 1491026-45-9
• Molecular Formula: C₃₃H₂₈NO₉P
• Molecular Weight: 613.56
• Mol file: 1491026-45-9.mol

Synonyms:C₃₃H₂₈NO₉P

Chemical Property of C₃₃H₂₈NO₉P

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₃₃H₂₈NO₉P

There total 8 articles about C₃₃H₂₈NO₉P which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C21H19NO6 (1491026-43-7) + chlorophosphoric acid diphenyl ester (2524-64-3) → C33H28NO9P (1491026-45-9)

Guidance literature:

With triethylamine; In toluene; at 20 ℃; for 5h;

Reference yield:

(4S,5R)-ethyl-5-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)-4-meth-yl-1,3,2-dioxathiolane-4-carboxylate 2,2-dioxide (879551-01-6) → C33H28NO9P (1491026-45-9)

Guidance literature:

Multi-step reaction with 5 steps

1.1: N,N-dimethyl-formamide; water / 5 h / 50 °C / Large scale

1.2: 30 °C / Large scale

2.1: hydrogenchloride / ethanol / 15 h / 20 - 30 °C

3.1: triethylamine; dmap / acetonitrile / 2.5 h / 0 - 25 °C

4.1: lithium tri-t-butoxyaluminum hydride / tetrahydrofuran / 2 h / -30 °C

5.1: triethylamine / toluene / 5 h / 20 °C

With hydrogenchloride; dmap; lithium tri-t-butoxyaluminum hydride; triethylamine; In tetrahydrofuran; ethanol; water; N,N-dimethyl-formamide; toluene; acetonitrile;

Reference yield:

C12H18NO8S(1-)*C16H36N(1+) → C33H28NO9P (1491026-45-9)

Guidance literature:

Multi-step reaction with 4 steps

1: hydrogenchloride / ethanol / 15 h / 20 - 30 °C

2: triethylamine; dmap / acetonitrile / 2.5 h / 0 - 25 °C

3: lithium tri-t-butoxyaluminum hydride / tetrahydrofuran / 2 h / -30 °C

4: triethylamine / toluene / 5 h / 20 °C

With hydrogenchloride; dmap; lithium tri-t-butoxyaluminum hydride; triethylamine; In tetrahydrofuran; ethanol; toluene; acetonitrile;

upstream raw materials:

C₁₁H₁₈O₄

(2S,3R)-3-[(4R)-2,2-dimethyl-[1,3]dioxolane-4-yl]-2,3-dihydroxy-2-methylpropionic acid ethyl ester

(4S,5R)-ethyl-5-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)-4-meth-yl-1,3,2-dioxathiolane-4-carboxylate 2,2-dioxide

C₁₁H₁₈O₇S

Downstream raw materials:

C₂₁H₁₈BrNO₅

Refernces